2. Gene
  3. ERO1A - endoplasmic reticulum oxidoreductase 1 alpha Gene

ERO1A - endoplasmic reticulum oxidoreductase 1 alpha Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：内质网氧化还原酶 1 α

种属: Homo sapiens

同用名: ERO1L; ERO1-L; ERO1LA; Ero1alpha; ERO1-alpha; ERO1-L-alpha

基因 ID: 30001 | 基因类型: protein coding

关于 ERO1A

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:52,639,915-52,695,558 (from NCBI)

This gene has 11 transcripts (splice variants), 197 orthologues and 1 paralogue. Broad expression in esophagus (RPKM 69.5), placenta (RPKM 19.1) and 21 other tissues.

功能概要

启用氧化还原酶活性。参与伴侣辅因子依赖性蛋白质重折叠。位于内质网。 [由基因组资源联盟提供，2022 年 4 月]

Enables oxidoreductase activity. Involved in chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

ERO1A 基因产物(14)

mRNA Protein Name
NM_001382464.1 NP_001369393.1 ERO1-like protein alpha isoform 1 precursor
NM_001382465.1 NP_001369394.1 ERO1-like protein alpha isoform 3 precursor
NM_001382466.1 NP_001369395.1 ERO1-like protein alpha isoform 4 precursor
NM_001382467.1 NP_001369396.1 ERO1-like protein alpha isoform 5 precursor
NM_001382468.1 NP_001369397.1 ERO1-like protein alpha isoform 6 precursor
NM_001382469.1 NP_001369398.1 ERO1-like protein alpha isoform 7 precursor
NM_001382470.1 NP_001369399.1 ERO1-like protein alpha isoform 8 precursor
NM_001382471.1 NP_001369400.1 ERO1-like protein alpha isoform 9 precursor
NM_001382472.1 NP_001369401.1 ERO1-like protein alpha isoform 10 precursor
NM_001382473.1 NP_001369402.1 ERO1-like protein alpha isoform 11 precursor
NM_001382474.1 NP_001369403.1 ERO1-like protein alpha isoform 12 precursor
NM_001382475.1 NP_001369404.1 ERO1-like protein alpha isoform 13 precursor
NM_001382476.1 NP_001369405.1 ERO1-like protein alpha isoform 14 precursor
NM_014584.3 NP_055399.1 ERO1-like protein alpha isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables oxidoreductase activity IDA
IDA: 通过直接分析推断
11707400 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
17170699 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell redox homeostasis IMP
IMP: 通过突变表型推断
29858230 GOA
involved in chaperone cofactor-dependent protein refolding IDA
IDA: 通过直接分析推断
11707400 GOA
involved in protein folding IMP
IMP: 通过突变表型推断
29858230 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi lumen IDA
IDA: 通过直接分析推断
29858230 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
10671517 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
29858230 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ERO1A 蛋白结构

ERO1

ERO1: Endoplasmic Reticulum Oxidoreductin 1 (ERO1) (60 - 457)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 468 a.a.
蛋白主名 其他名称

ERO1-like protein alpha

endoplasmic oxidoreductin-1-like protein

重组 ERO1A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70893 ERO1L Protein, Human (HEK293, His) Q96HE7 (E24-H468) ≥95%

关联疾病

疾病名称 别名
Cholera

Vibrio Cholerae Infection

Cholera - Vibrio Cholerae

Cholera Due To Vibrio Cholerae

Vibrio Cholerae

Cholera Syndrome

Asiatic Cholera

Epidemic Cholera
Hypoascorbemia

Scurvy

Ascorbic Acid Deficiency

Vitamin C Deficiency

Vitamin C, Inability To Synthesize

Deficiency Of Vitamin C

Scorbutus

Vitamin C
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04511 ERO1A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ERO1A VGNC VGNC:72266
Mus musculus ERO1A MGD MGI:1354385
Bos taurus ERO1A VGNC VGNC:28594
Canis familiaris ERO1A VGNC VGNC:40466
Rattus norvegicus ERO1A RGD RGD:621713
Felis catus ERO1A VGNC VGNC:61954
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