1. Gene
  2. EIF4E3 - eukaryotic translation initiation factor 4E family member 3 Gene

EIF4E3 - eukaryotic translation initiation factor 4E family member 3 Gene

中文名称:真核翻译起始因子 4E 家族成员 3

种属: Homo sapiens

同用名: eIF-4E3; eIF4E-3

基因 ID: 317649 | 基因类型: protein coding

关于 EIF4E3

Cytogenetic location: 3p13 Genomic coordinates (GRCh38): 3:71,659,363-71,754,773 (from NCBI)

This gene has 10 transcripts (splice variants), 263 orthologues and 3 paralogues. Ubiquitous expression in fat (RPKM 11.9), brain (RPKM 7.2) and 25 other tissues.

功能概要

EIF4E3 属于 EIF4E 翻译起始因子家族,它与 mRNA 的 5-prime 帽结构相互作用并将 mRNA 募集到核糖体 (Joshi 等人,2004 [PubMed 15153109]) 。[OMIM 提供,2008 年 3 月]

EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]

EIF4E3 基因产物(5)

mRNA Protein Name
NM_001134649.3 NP_001128121.1 eukaryotic translation initiation factor 4E type 3 isoform b
NM_001134650.1 NP_001128122.1 eukaryotic translation initiation factor 4E type 3 isoform b
NM_001134651.2 NP_001128123.1 eukaryotic translation initiation factor 4E type 3 isoform a
NM_001282886.2 NP_001269815.1 eukaryotic translation initiation factor 4E type 3 isoform b
NM_173359.5 NP_775495.1 eukaryotic translation initiation factor 4E type 3 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

EIF4E3 蛋白结构

IF4E

IF4E: Eukaryotic initiation factor 4E (48 - 211)

  • 0
  • 100
  • 200
  • 224 a.a.
蛋白主名 其他名称

eukaryotic translation initiation factor 4E type 3

关联疾病

疾病名称 别名
Thymus Lymphoma

Thymic Lymphoma

Eyelid Disease

Eyelid Diseases

Eyelid Disorders

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris EIF4E3 VGNC VGNC:40285
Rattus norvegicus EIF4E3 RGD RGD:1586185
Felis catus EIF4E3 VGNC VGNC:61792
Mus musculus EIF4E3 MGD MGI:1914142
Bos taurus EIF4E3 VGNC VGNC:28411