2. Gene
  3. TRIM72 - tripartite motif containing 72 Gene

TRIM72 - tripartite motif containing 72 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含三方基序 72

种属: Homo sapiens

同用名: MG53

基因 ID: 493829 | 基因类型: protein coding

关于 TRIM72

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:31,214,119-31,231,537 (from NCBI)

This gene has 2 transcripts (splice variants), 104 orthologues and 80 paralogues. Biased expression in prostate (RPKM 2.0), esophagus (RPKM 0.3) and 1 other tissue.

功能概要

实现相同的蛋白质结合活性。预计参与多个过程，包括细胞蛋白质代谢过程；质膜修复；和蛋白质同源寡聚化。预测作用于胰岛素受体信号通路的上游或负调节范围内；胰岛素样生长因子受体信号通路的负调控；和肌管分化的负调节。预测位于细胞质囊泡膜。预计在细胞质和肌膜中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; plasma membrane repair; and protein homooligomerization. Predicted to act upstream of or within negative regulation of Insulin Receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; and negative regulation of myotube differentiation. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasm and sarcolemma. [provided by Alliance of Genome Resources, Apr 2022]

TRIM72 基因产物(1)

mRNA Protein Name
NM_001008274.4 NP_001008275.2 tripartite motif-containing protein 72

TRIM72 蛋白结构

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (14 - 56)

zf-B_box

zf-B_box: B-box zinc finger (84 - 121)

PRY

PRY: SPRY-associated domain (291 - 339)

SPRY

SPRY: SPRY domain (343 - 457)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 477 a.a.
蛋白主名 其他名称

tripartite motif-containing protein 72

mitsugumin-53

TRIM72 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRIM72 Q6ZMU5 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
种属内
TRIM72 Q6ZMU5 TCF12 Homo sapiens Q99081-3
Validated Y2H
32296183
种属内
TRIM72 Q6ZMU5 TCF12 Homo sapiens Q99081-3
Y2H Array
32296183
种属内
TRIM72 Q6ZMU5 TCF12 Homo sapiens Q99081-3
Y2H Prey Pooling
32296183
种属内
TRIM72 Q6ZMU5 PPP3CA Homo sapiens Q08209-2
Y2H Array
32296183
种属内
TRIM72 Q6ZMU5 PPP3CA Homo sapiens Q08209-2
Y2H Prey Pooling
32296183
种属内
TRIM72 Q6ZMU5 NMI Homo sapiens Q13287
Y2H Array
32296183
种属内
TRIM72 Q6ZMU5 MZT1 Homo sapiens Q08AG7
Y2H Prey Pooling
32296183
种属内
TRIM72 Q6ZMU5 MED21 Homo sapiens Q13503
Y2H Prey Pooling
32296183
种属内
TRIM72 Q6ZMU5 TCF12 Homo sapiens Q99081
Y2H Prey Pooling
25416956
种属内
TRIM72 Q6ZMU5 MZT1 Homo sapiens Q08AG7
Y2H Array
32296183
种属内
TRIM72 Q6ZMU5 C1orf216 Homo sapiens Q8TAB5
Validated Y2H
32296183
种属内
TRIM72 Q6ZMU5 TCF12 Homo sapiens Q99081
Y2H Array
25416956
种属内
TRIM72 Q6ZMU5 NMI Homo sapiens Q13287
Y2H Prey Pooling
32296183
种属内
TRIM72 Q6ZMU5 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
种属内
TRIM72 Q6ZMU5 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
种属内
TRIM72 Q6ZMU5 ZNF655 Homo sapiens Q8N720
Validated Y2H
32296183
种属内
TRIM72 Q6ZMU5 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Miyoshi Muscular Dystrophy

Distal Myopathy

Distal Muscular Dystrophy

Miyoshi Myopathy

Distal Myopathies

Dystrophy, Muscular, Miyoshi

Myopathy, Distal

Distal Muscular Dystrophies
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2b

Lgmd2b

Lgmd3

Limb-Girdle Muscular Dystrophy Due To Dysferlin Deficiency

Limb-Girdle Muscular Dystrophy Type 3

Muscular Dystrophy, Limb-Girdle, Type 2b
Glycogen Storage Disease Vii

Glycogen Storage Disease Type Vii

Muscle Phosphofructokinase Deficiency

Tarui Disease

GSD7

Pfkm Deficiency

Gsd Vii

Glycogen Storage Disease, Type Vii

Glycogen Storage Disease Type 7

Phosphofructokinase Deficiency

Glycogenosis Type Vii

Phosphofructokinase Myopathy

Glycogenosis 7

Glycogen Storage Disease Due To Muscle Phosphofructokinase Deficiency

Gsd Due To Muscle Phosphofructokinase Deficiency

Gsd Type 7

Gsd Type Vii

Glycogenosis Due To Muscle Phosphofructokinase Deficiency

Glycogenosis Type 7

Glycogen Storage Disease 7

Gsd-Vii

Storage Disease, Glycogen, Type Vii
Autosomal Recessive Limb-Girdle Muscular Dystrophy

Muscular Dystrophy, Limb-Girdle, Autosomal Recessive
Limb-Girdle Muscular Dystrophy

Lgmd

Limb Girdle Muscular Dystrophy

Muscular Dystrophies, Limb-Girdle

Erb'S Muscular Dystrophy

Leyden-Mbius Muscular Dystrophy

Limb-Girdle Syndrome

Myopathic Limb-Girdle Syndrome

Limb Girdle

Muscular Dystrophy Limb-Girdle

Dystrophy, Muscular, Limb-Girdle

Lgmd - [Limb-Girdle Muscular Dystrophy]

Limb Girdle Muscle Dystrophy

Limb-Girdle Myopathy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15071 TRIM72 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus TRIM72 MGD MGI:3612190
Canis familiaris TRIM72 VGNC VGNC:47838
Rattus norvegicus TRIM72 RGD RGD:1562778
Macaca mulatta TRIM72 VGNC VGNC:79927
Bos taurus TRIM72 VGNC VGNC:58423
Felis catus TRIM72 VGNC VGNC:66554
Others TRIM72 NCBI
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