2. Gene
  3. MZT1 - mitotic spindle organizing protein 1 Gene

MZT1 - mitotic spindle organizing protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：有丝分裂纺锤体组织蛋白 1

种属: Homo sapiens

同用名: MOZART1; C13orf37

基因 ID: 440145 | 基因类型: protein coding

关于 MZT1

Cytogenetic location: 13q21.33 Genomic coordinates (GRCh38): 13:72,708,367-72,727,629 (from NCBI)

This gene has 1 transcript (splice variant) and 209 orthologues. Ubiquitous expression in brain (RPKM 11.3), bone marrow (RPKM 9.3) and 25 other tissues.

功能概要

参与 γ-微管蛋白复合物定位。位于中心体和纺锤体。 γ-微管蛋白大复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Involved in gamma-tubulin complex localization. Located in centrosome and spindle. Part of gamma-tubulin large complex. [provided by Alliance of Genome Resources, Apr 2022]

MZT1 基因产物(1)

mRNA Protein Name
NM_001071775.3 NP_001065243.1 mitotic-spindle organizing protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20360068 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in gamma-tubulin complex localization IMP
IMP: 通过突变表型推断
20360068 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
20360068 GOA
part of gamma-tubulin ring complex IDA
IDA: 通过直接分析推断
20360068 GOA
located in spindle IDA
IDA: 通过直接分析推断
20360068 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MZT1 蛋白结构

MOZART1

MOZART1: Mitotic-spindle organizing gamma-tubulin ring associated (22 - 68)

  • 0
  • 82 a.a.
蛋白主名 其他名称

mitotic-spindle organizing protein 1

mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1

MZT1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MZT1 Q08AG7 TRIM72 Homo sapiens Q6ZMU5
Validated Y2H
32296183
Intra MZT1 Q08AG7 TUBG1 Homo sapiens P23258
Anti Tag CoIP
33961781
Intra MZT1 Q08AG7 TUBG1 Homo sapiens P23258
Anti Tag CoIP
26496610
Intra MZT1 Q08AG7 TUBG1 Homo sapiens P23258
Anti Tag CoIP
28514442
Intra MZT1 Q08AG7 TUBG1 Homo sapiens P23258
TAP
20360068
Intra MZT1 Q08AG7 TUBG1 Homo sapiens P23258
Density Sedimentation
20360068
Intra MZT1 Q08AG7 CYGB Homo sapiens Q8WWM9
Validated Y2H
32296183
Intra MZT1 Q08AG7 CINP Homo sapiens Q9BW66
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Macular Degeneration, Age-Related, 2

Age Related Macular Degeneration 2

ARMD2

Macular Degeneration, Senile

Maculopathy, Age-Related, 2

Macular Degeneration, Age-Related, 2, Susceptibility To

Macular Degeneration, Age-Related, Type 2
Omodysplasia 1

OMOD1

Autosomal Recessive Omodysplasia

Omodysplasia Autosomal Recessive

Omodysplasia Generalized Form

Omodysplasia Type 1

Omodysplasia, Generalized Form

Omodysplasia, Autosomal Recessive

Micromelic Dysplasia, Congenital, With Dislocation Of Radius

Micromelic Dysplasia Congenita With Dislocation Of Radius

Micromelic Dysplasia-Dislocation Of Radius Syndrome

Micromelic Dysplasia Congenital With Dislocation Of Radius

Omodysplasia, Type 1
Abcd Syndrome

ABCDS

Albinism, Black Lock, Cell Migration Disorder Of The Neurocytes Of The Gut, And Deafness

Albinism, Black Lock, Cell Migration Disorder Of The Neurocytes Of The Gut And Deafness
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08977 MZT1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus MZT1 VGNC VGNC:31851
Rattus norvegicus MZT1 RGD RGD:1592140
Macaca mulatta MZT1 VGNC VGNC:106274
Felis catus MZT1 VGNC VGNC:102260
Canis familiaris MZT1 VGNC VGNC:43595
Mus musculus MZT1 MGD MGI:1924039
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