1. Gene
  2. Fbxl3 - F-box and leucine-rich repeat protein 3 Gene

Fbxl3 - F-box and leucine-rich repeat protein 3 Gene

种属: Mus musculus

同用名: FBK; Ovtm; Fbl3a; Fbxl3a; Play68

基因 ID: 50789 | 基因类型: protein coding

关于 Fbxl3

功能概要

Contributes to ubiquitin-protein transferase activity. Involved in cellular protein metabolic process; entrainment of circadian clock by photoperiod; and protein destabilization. Located in cytosol and nucleus. Is expressed in embryo; extraembryonic component; inner cell mass; and trophectoderm. Orthologous to human FBXL3 (F-box and leucine rich repeat protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Fbxl3 基因产物(5)

mRNA Protein Name
NM_001347600.1 NP_001334529.1 F-box/LRR-repeat protein 3 isoform 2
NM_001347601.1 NP_001334530.1 F-box/LRR-repeat protein 3 isoform 2
NM_001360341.1 NP_001347270.1 F-box/LRR-repeat protein 3 isoform 1
NM_001360342.1 NP_001347271.1 F-box/LRR-repeat protein 3 isoform 1
NM_015822.3 NP_056637.1 F-box/LRR-repeat protein 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17462724 MGI
contributes to ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
17462724 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
23452855 MGI
involved in entrainment of circadian clock by photoperiod IMP
IMP: 通过突变表型推断
23452855 MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
17462724 MGI
involved in protein destabilization IMP
IMP: 通过突变表型推断
23616524 MGI
involved in protein ubiquitination IDA
IDA: 通过直接分析推断
23452855 MGI
involved in protein ubiquitination IMP
IMP: 通过突变表型推断
26776516 MGI
involved in regulation of circadian rhythm IMP
IMP: 通过突变表型推断
17462724 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
23452855 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17463252 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

F-box/LRR-repeat protein 3

F-box and leucine-rich repeat protein 3a

F-box/LRR-repeat protein 3A

protein after-hours

protein overtime

Fbxl3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Fbxl3 Q8C4V4 Cry1 Mus musculus P97784
Anti Tag CoIP
23452855
Intra Fbxl3 Q8C4V4 Cry1 Mus musculus P97784
Anti Tag CoIP
17462724
Intra Fbxl3 Q8C4V4 Cry1 Mus musculus P97784
Anti Tag CoIP
23452856
Intra Fbxl3 Q8C4V4 Cry2 Mus musculus Q9R194
Anti Tag CoIP
17462724
Intra Fbxl3 Q8C4V4 Cry2 Mus musculus Q9R194
Anti Tag CoIP
23452856
Intra Fbxl3 Q8C4V4 Per2 Mus musculus O54943
Anti Tag CoIP
23452855
Cross Fbxl3 Q8C4V4 SKP1 Homo sapiens P63208
Anti Tag CoIP
23452856
Cross Fbxl3 Q8C4V4 CUL1 Homo sapiens Q13616
Anti Tag CoIP
23452856
Cross Fbxl3 Q8C4V4 CUL1 Homo sapiens Q13616
BiFC
23452855
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fbxl3 NCBI NCBI:26224