BTBD1 - BTB domain containing 1 Gene

中文名称：含 BTB 域 1

种属: Homo sapiens

同用名: C15orf1; NS5ATP8

关于 BTBD1

功能概要

该基因编码的蛋白质的 C 端结合拓扑异构酶 I。N 端包含富含脯氨酸的区域和 BTB/POZ 结构域 (广泛复合物、Tramtrack 和 bric a brac/Pox 病毒和锌指) ，两者其中通常参与蛋白质-蛋白质相互作用。在亚细胞中，蛋白质定位于细胞质体。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 7 月]

The C-terminus of the protein encoded by this gene binds Topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]