1. Gene
  2. Sstr2 - somatostatin receptor 2 Gene

Sstr2 - somatostatin receptor 2 Gene

中文名称:生长抑素受体 2

种属: Rattus norvegicus

同用名: Smstr2

基因 ID: 54305 | 基因类型: protein coding

关于 Sstr2

Primary_assembly 10: 98,664,216-98,674,351 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 264 orthologues, 14 paralogues and is associated with 7 phenotypes. Biased expression in Adrenal (RPKM 48.4), Brain (RPKM 31.2) and 3 other tissues.

功能概要

该基因编码的蛋白可启动 PDZ 结构域结合活性和生长抑素受体活性。参与多个过程,包括大脑发育;细胞对脂质的反应;和蠕动。位于细胞质和质膜中。与人类 SSTR2(生长抑素受体 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables PDZ domain binding activity and Somatostatin Receptor activity. Involved in several processes, including brain development; cellular response to lipid; and peristalsis. Located in cytoplasm and plasma membrane. Orthologous to human SSTR2 (Somatostatin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sstr2 基因产物(1)

mRNA Protein Name
NM_019348.2 NP_062221.1 somatostatin receptor type 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
10551867 RGD
enables somatostatin receptor activity IDA
IDA: 通过直接分析推断
1374909 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to estradiol stimulus IEP
IEP: 通过表达模式推断
9564833 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
14512709 RGD
involved in cerebellum development IEP
IEP: 通过表达模式推断
9166718 RGD
involved in forebrain development IEP
IEP: 通过表达模式推断
10805921 RGD
involved in peristalsis IMP
IMP: 通过突变表型推断
12504886 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
7956902 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
9421433 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Sstr2 蛋白结构

7tmA_SSTR2

7tmA_SSTR2: cd15971 (43 - 322)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (44 - 70)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (77 - 103)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (114 - 144)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (156 - 178)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (204 - 233)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (248 - 278)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (290 - 315)

  • 0
  • 100
  • 200
  • 300
  • 369 a.a.
蛋白主名 其他名称

somatostatin receptor type 2

SRIF-1

SS-2-R

SS2-R

SS2R

somatostatin receptor subtype 2

somatotropin release-inhibiting factor receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sstr2 NCBI NCBI:6752