LPCAT2 - lysophosphatidylcholine acyltransferase 2 Gene

中文名称：溶血磷脂酰胆碱酰基转移酶 2

种属: Homo sapiens

同用名: AYTL1; LPLAT9; AGPAT11; LysoPAFAT

关于 LPCAT2

功能概要

该基因编码溶血磷脂酰基转移酶家族的一个成员。编码的酶可能以两种方式发挥作用：催化血小板活化因子 (1-O-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱) 从 1-O-烷基-sn-甘油-3-磷酸胆碱，并催化从花生四烯酰辅酶 A 和溶血磷脂酰胆碱合成甘油磷脂前体。编码的蛋白质可能在膜生物发生和炎症细胞中血小板活化因子的产生中发挥作用。该酶可定位于内质网和高尔基体。[RefSeq 提供，2009 年 2 月]

This gene encodes a member of the lysophospholipid Acyltransferase family. The encoded Enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The Enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009]