2. Gene
  3. TESC - tescalcin Gene

TESC - tescalcin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：钙素

种属: Homo sapiens

同用名: TSC; CHP3

基因 ID: 54997 | 基因类型: protein coding

关于 TESC

Cytogenetic location: 12q24.22 Genomic coordinates (GRCh38): 12:117,038,923-117,099,416 (from NCBI)

This gene has 8 transcripts (splice variants), 288 orthologues and 8 paralogues. Broad expression in salivary gland (RPKM 66.0), stomach (RPKM 63.6) and 14 other tissues.

功能概要

启用钙离子结合活性。参与多个过程，包括细胞对视黄酸的反应；大分子代谢过程的正向调控；和骨髓细胞分化的正调节。位于几种细胞成分中，包括细胞质；片状足；和核质。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium ion binding activity. Involved in several processes, including cellular response to retinoic acid; positive regulation of macromolecule metabolic process; and positive regulation of myeloid cell differentiation. Located in several cellular components, including cytosol; lamellipodium; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TESC 基因产物(2)

mRNA Protein Name
NM_001168325.2 NP_001161797.1 calcineurin B homologous protein 3 isoform 2
NM_017899.4 NP_060369.3 calcineurin B homologous protein 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
11696366 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
11696366 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to retinoic acid IDA
IDA: 通过直接分析推断
20060826 GOA
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17717601 GOA
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17717601 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
17717601 GOA
involved in positive regulation of granulocyte differentiation IDA
IDA: 通过直接分析推断
20060826 GOA
involved in positive regulation of megakaryocyte differentiation IMP
IMP: 通过突变表型推断
17717601 GOA
involved in positive regulation of sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
18321853 GOA
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
18321853 GOA
involved in protein maturation IDA
IDA: 通过直接分析推断
18321853 GOA
involved in protein stabilization IDA
IDA: 通过直接分析推断
18321853 GOA
involved in regulation of cell adhesion mediated by integrin IMP
IMP: 通过突变表型推断
17717601 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18321853 GOA
located in lamellipodium IDA
IDA: 通过直接分析推断
11696366 GOA
located in nucleus IDA
IDA: 通过直接分析推断
17717601 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
18321853 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TESC 蛋白结构

EF-hand_6

EF-hand_6: EF-hand domain (114 - 139)

  • 0
  • 100
  • 200
  • 214 a.a.
蛋白主名 其他名称

calcineurin B homologous protein 3

calcineurin-like EF hand protein 3

TESC 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TESC Q96BS2 WBP11 Homo sapiens Q9Y2W2
Validated Y2H
25416956
Intra TESC Q96BS2 WBP11 Homo sapiens Q9Y2W2
Y2H Prey Pooling
25416956
Intra TESC Q96BS2 HMG20A Homo sapiens Q9NP66
Pull Down
16189514
Intra TESC Q96BS2 SLC9A1 Homo sapiens P19634
Fluorescence
31912575
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14379 TESC Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TESC VGNC VGNC:35753
Canis familiaris TESC VGNC VGNC:52973
Macaca mulatta TESC VGNC VGNC:79571
Felis catus TESC VGNC VGNC:66088
Mus musculus TESC MGD MGI:1930803
Rattus norvegicus TESC RGD RGD:1566317
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