2. Gene
  3. SAMD4B - sterile alpha motif domain containing 4B Gene

SAMD4B - sterile alpha motif domain containing 4B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含无菌 alpha 基序结构域 4B

种属: Homo sapiens

同用名: SMGB; Smaug2

基因 ID: 55095 | 基因类型: protein coding

关于 SAMD4B

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,342,421-39,390,764 (from NCBI)

This gene has 12 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 7.6), ovary (RPKM 7.3) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与核转录的 mRNA poly (A) 尾部缩短。预测作用于小脑神经元发育的上游或内部。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

SAMD4B 基因产物(30)

mRNA Protein Name
NM_001303614.2 NP_001290543.1 protein Smaug homolog 2 isoform b
NM_001384565.1 NP_001371494.1 protein Smaug homolog 2 isoform a
NM_001384566.1 NP_001371495.1 protein Smaug homolog 2 isoform a
NM_001384568.1 NP_001371497.1 protein Smaug homolog 2 isoform a
NM_001384569.1 NP_001371498.1 protein Smaug homolog 2 isoform a
NM_001384570.1 NP_001371499.1 protein Smaug homolog 2 isoform a
NM_001384571.1 NP_001371500.1 protein Smaug homolog 2 isoform a
NM_001384573.1 NP_001371502.1 protein Smaug homolog 2 isoform a
NM_001384574.2 NP_001371503.1 protein Smaug homolog 2 isoform a
NM_001384575.1 NP_001371504.1 protein Smaug homolog 2 isoform a
NM_001384576.1 NP_001371505.1 protein Smaug homolog 2 isoform a
NM_001384577.1 NP_001371506.1 protein Smaug homolog 2 isoform a
NM_001384578.1 NP_001371507.1 protein Smaug homolog 2 isoform a
NM_001384580.1 NP_001371509.1 protein Smaug homolog 2 isoform b
NM_001384581.1 NP_001371510.1 protein Smaug homolog 2 isoform b
NM_001384582.1 NP_001371511.1 protein Smaug homolog 2 isoform b
NM_001384583.1 NP_001371512.1 protein Smaug homolog 2 isoform b
NM_001384584.1 NP_001371513.1 protein Smaug homolog 2 isoform b
NM_001384585.1 NP_001371514.1 protein Smaug homolog 2 isoform c
NM_001384586.1 NP_001371515.1 protein Smaug homolog 2 isoform c
NM_001384587.1 NP_001371516.1 protein Smaug homolog 2 isoform c
NM_001384588.1 NP_001371517.1 protein Smaug homolog 2 isoform c
NM_001384589.1 NP_001371518.1 protein Smaug homolog 2 isoform c
NM_001384590.1 NP_001371519.1 protein Smaug homolog 2 isoform c
NM_001384591.1 NP_001371520.1 protein Smaug homolog 2 isoform c
NM_001384592.1 NP_001371521.1 protein Smaug homolog 2 isoform c
NM_001384593.1 NP_001371522.1 protein Smaug homolog 2 isoform c
NM_001384594.1 NP_001371523.1 protein Smaug homolog 2 isoform c
NM_001384595.1 NP_001371524.1 protein Smaug homolog 2 isoform d
NM_018028.4 NP_060498.2 protein Smaug homolog 2 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15161933 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SAMD4B 蛋白结构

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (300 - 357)

  • 0
  • 200
  • 400
  • 600
  • 694 a.a.
蛋白主名 其他名称

protein Smaug homolog 2

SAM domain-containing protein 4B

SAMD4B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SAMD4B Q5PRF9 BCL2L10 Homo sapiens Q9HD36
Validated Y2H
32296183
种属内
SAMD4B Q5PRF9 YWHAZ Homo sapiens P63104
Pull Down
15161933
种属内
SAMD4B Q5PRF9 YWHAZ Homo sapiens P63104
Anti Tag CoIP
28514442
种属内
SAMD4B Q5PRF9 YWHAE Homo sapiens P62258
Anti Tag CoIP
33961781
种属内
SAMD4B Q5PRF9 YWHAE Homo sapiens P62258
Anti Tag CoIP
28514442
种属内
SAMD4B Q5PRF9 YWHAE Homo sapiens P62258
Crosslink
36931259
种属内
SAMD4B Q5PRF9 USP53 Homo sapiens Q70EK8
Validated Y2H
32296183
种属内
SAMD4B Q5PRF9 LRRC8E Homo sapiens Q6NSJ5
Validated Y2H
32296183
种属内
SAMD4B Q5PRF9 RSRC2 Homo sapiens Q7L4I2
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Protoplasmic Astrocytoma

Protoplasmic Astrocytic Tumor

Astrocytoma Protoplasmic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12427 SAMD4B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SAMD4B RGD RGD:1305597
Felis catus SAMD4B VGNC VGNC:64863
Bos taurus SAMD4B VGNC VGNC:34273
Canis familiaris SAMD4B VGNC VGNC:45853
Mus musculus SAMD4B MGD MGI:2448542
Macaca mulatta SAMD4B VGNC VGNC:77102
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z