1. Gene
  2. CCDC25 - coiled-coil domain containing 25 Gene

CCDC25 - coiled-coil domain containing 25 Gene

中文名称:含卷曲螺旋结构域 25

种属: Homo sapiens

基因 ID: 55246 | 基因类型: protein coding

关于 CCDC25

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:27,733,316-27,772,640 (from NCBI)

This gene has 11 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in duodenum (RPKM 17.8), small intestine (RPKM 15.9) and 25 other tissues.

功能概要

启用 DNA 结合活性。参与细胞运动的正调节。位于内膜系统。是质膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables DNA binding activity. Involved in positive regulation of cell motility. Located in endomembrane system. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CCDC25 基因产物(4)

mRNA Protein Name
NM_001304529.2 NP_001291458.1 coiled-coil domain-containing protein 25 isoform 2
NM_001304530.2 NP_001291459.1 coiled-coil domain-containing protein 25 isoform 3
NM_001304532.2 NP_001291461.1 coiled-coil domain-containing protein 25 isoform 4
NM_018246.3 NP_060716.2 coiled-coil domain-containing protein 25 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
32528174 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell motility IDA
IDA: 通过直接分析推断
32528174 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endomembrane system IDA
IDA: 通过直接分析推断
32528174 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
32528174 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CCDC25 蛋白结构

DUF814

DUF814: Domain of unknown function (DUF814) (11 - 100)

  • 0
  • 100
  • 208 a.a.
蛋白主名 其他名称

coiled-coil domain-containing protein 25

关联疾病

疾病名称 别名
Chronic Cholangitis
Colorectal Cancer, Hereditary Nonpolyposis, Type 2

HNPCC2

Fcc2

Coca2

Hereditary Nonpolyposis Colorectal Cancer Type 2

Colon Cancer, Familial Nonpolyposis, Type 2

Familial Nonpolyposis Colon Cancer Type 2

Hereditary Non-Polyposis Colorectal Cancer 2

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 2

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CCDC25 MGD MGI:1914429
Macaca mulatta CCDC25 VGNC VGNC:99468
Bos taurus CCDC25 VGNC VGNC:26888
Rattus norvegicus CCDC25 RGD RGD:1307689
Felis catus CCDC25 VGNC VGNC:78463