2. Gene
  3. LUC7L - LUC7 like Gene

LUC7L - LUC7 like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：LUC7 样

种属: Homo sapiens

同用名: Luc7; SR+89; LUC7B1; hLuc7B1

基因 ID: 55692 | 基因类型: protein coding

关于 LUC7L

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:188,990-229,449 (from NCBI)

This gene has 21 transcripts (splice variants), 203 orthologues and 2 paralogues. Ubiquitous expression in endometrium (RPKM 18.6), spleen (RPKM 15.0) and 25 other tissues.

功能概要

LUC7L 基因可能代表哺乳动物异染色质基因，编码推定的 RNA 结合蛋白，类似于 U1 snRNP 剪接复合物的酵母 Luc7p 亚基，通常需要 5-prime 剪接位点选择 (Tufarelli 等人，2001 [PubMed 11170747) ]) .[OMIM 提供，2008 年 3 月]

The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001 [PubMed 11170747]).[supplied by OMIM, Mar 2008]

LUC7L 基因产物(4)

mRNA Protein Name
NM_001320226.2 NP_001307155.1 putative RNA-binding protein Luc7-like 1 isoform a
NM_001330420.2 NP_001317349.1 putative RNA-binding protein Luc7-like 1 isoform c
NM_018032.5 NP_060502.1 putative RNA-binding protein Luc7-like 1 isoform a
NM_201412.3 NP_958815.1 putative RNA-binding protein Luc7-like 1 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
22365833 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
22365833 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LUC7L 蛋白结构

LUC7

LUC7: LUC7 N_terminus (5 - 247)

  • 0
  • 100
  • 200
  • 300
  • 371 a.a.
蛋白主名 其他名称

putative RNA-binding protein Luc7-like 1

putative SR protein LUC7B1

LUC7L 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra LUC7L Q9NQ29 RNASEH1 Homo sapiens O60930
Anti Tag CoIP
33961781
Intra LUC7L Q9NQ29 NFKBIL1 Homo sapiens Q9UBC1
Anti Tag CoIP
33961781
Intra LUC7L Q9NQ29 SRPK2 Homo sapiens P78362
Anti Tag CoIP
33961781
Intra LUC7L Q9NQ29 SRPK1 Homo sapiens Q96SB4
Anti Tag CoIP
33961781
Intra LUC7L Q9NQ29 SRPK1 Homo sapiens Q96SB4
Protein Kinase Assay
23602568
Intra LUC7L Q9NQ29 CLK2 Homo sapiens P49760
Anti Tag CoIP
33961781
Intra LUC7L Q9NQ29 TNPO3 Homo sapiens Q9Y5L0
Anti Tag CoIP
33961781
Intra LUC7L Q9NQ29 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra LUC7L Q9NQ29 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra LUC7L Q9NQ29 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Alpha-Thalassemia

Alpha Thalassemia

Alpha Thalassaemia

Alpha Plus Thalassemia

Thalassemia, Alpha-

Thalassemias, Alpha-

A-Thalassemia

Α-Thalassemia

A-THAL

Thalassemia

Alpha Thalassaemia Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07888 LUC7L Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07889 LUC7L2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07890 LUC7L3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus LUC7L MGD MGI:1914228
Canis familiaris LUC7L VGNC VGNC:42863
Bos taurus LUC7L VGNC VGNC:31079
Rattus norvegicus LUC7L RGD RGD:1307542
Macaca mulatta LUC7L VGNC VGNC:74461
Felis catus LUC7L VGNC VGNC:80589
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