CCL28 - C-C motif chemokine ligand 28 Gene

中文名称：CC 基序趋化因子配体 28

种属: Homo sapiens

同用名: MEC; CCK1; SCYA28

关于 CCL28

功能概要

这种抗菌基因属于小细胞因子 CC 基因的亚家族。细胞因子是参与免疫调节和炎症过程的分泌蛋白家族。 CC 细胞因子是以两个相邻的半胱氨酸为特征的蛋白质。由该基因编码的细胞因子显示出对静息 CD4 或 CD8 T 细胞和嗜酸性粒细胞的趋化活性。该基因的产物与趋化因子受体 CCR3 和 CCR10 结合。这种趋化因子可能在皮外上皮组织 (包括各种粘膜器官) 的生理学中发挥作用。已发现该基因编码两种不同亚型的多个转录变体。[RefSeq 提供，2014 年 9 月]

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]