THAP10 - THAP domain containing 10 Gene

中文名称：含 THAP 域 10

种属: Homo sapiens

基因 ID: 56906 | 基因类型: protein coding

关于 THAP10

Cytogenetic location: 15q23 Genomic coordinates (GRCh38): 15:70,881,342-70,892,433 (from NCBI)

This gene has 2 transcripts (splice variants), 169 orthologues and 18 paralogues. Ubiquitous expression in brain (RPKM 3.1), thyroid (RPKM 2.1) and 24 other tissues.

功能概要

该基因编码一个共享 N 末端 Thanatos 相关结构域的蛋白质家族成员。 Thanatos 相关结构域包含类似于 DNA 结合结构域的锌指特征。该基因是 15 号染色体长臂上双向基因对的一部分，受雌激素调节，可能在乳腺癌中发挥作用。[RefSeq 提供，2010 年 11 月]

This gene encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. The Thanatos-associated domain contains a zinc finger signature similar to DNA-binding domains. This gene is part of a bidirectional gene pair on the long arm of chromosome 15 that is regulated by estrogen and may play a role in breast Cancer. [provided by RefSeq, Nov 2010]

THAP10 基因产物(1)

mRNA	Protein	Name
NM_020147.4	NP_064532.1	THAP domain-containing protein 10

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	21516116	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

THAP10 蛋白结构

THAP

0
100
200
257 a.a.

蛋白主名

其他名称

THAP domain-containing protein 10

THAP10 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	THAP10	Q9P2Z0	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	25416956
种属内	THAP10	Q9P2Z0	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	25416956
种属内	THAP10	Q9P2Z0	KRTAP10-9	Homo sapiens	P60411	Y2H Array	25416956
种属内	THAP10	Q9P2Z0	KRTAP10-9	Homo sapiens	P60411	Y2H Prey Pooling	25416956
种属内	THAP10	Q9P2Z0	KRTAP10-5	Homo sapiens	P60370	Y2H Array	25416956
种属内	THAP10	Q9P2Z0	DYNLL1	Homo sapiens	P63167	Y2H Prey Pooling	32296183
种属内	THAP10	Q9P2Z0	DYNLL1	Homo sapiens	P63167	Y2H Array	32296183
种属内	THAP10	Q9P2Z0	PSME3	Homo sapiens	P61289	Y2H Array	32296183
种属内	THAP10	Q9P2Z0	PSME3	Homo sapiens	P61289	Y2H Prey Pooling	32296183
种属内	THAP10	Q9P2Z0	PTS	Homo sapiens	Q03393	Y2H Array	25416956
种属内	THAP10	Q9P2Z0	PTS	Homo sapiens	Q03393	Validated Y2H	25416956
种属内	THAP10	Q9P2Z0	PTS	Homo sapiens	Q03393	Y2H Prey Pooling	25416956
种属内	THAP10	Q9P2Z0	LZTS2	Homo sapiens	Q9BRK4	Validated Y2H	25416956
种属内	THAP10	Q9P2Z0	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Array	32296183
种属内	THAP10	Q9P2Z0	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Prey Pooling	32296183
种属内	THAP10	Q9P2Z0	NME7	Homo sapiens	Q9Y5B8	Validated Y2H	32296183
种属内	THAP10	Q9P2Z0	CCNDBP1	Homo sapiens	O95273	Y2H Array	25416956
种属内	THAP10	Q9P2Z0	CCNDBP1	Homo sapiens	O95273	Y2H	21516116
种属内	THAP10	Q9P2Z0	CCNDBP1	Homo sapiens	O95273	Y2H Array	31515488
种属内	THAP10	Q9P2Z0	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	25416956
种属内	THAP10	Q9P2Z0	CCNDBP1	Homo sapiens	O95273	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

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THAP10 - THAP domain containing 10 Gene

关于 THAP10

功能概要

THAP10 基因产物(1)

THAP10 蛋白结构

THAP10 蛋白互作信息

关联疾病

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THAP10 - THAP domain containing 10 Gene

关于 THAP10

功能概要

THAP10 基因产物(1)

THAP10 蛋白结构

THAP10 蛋白互作信息

关联疾病

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热门区域

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