2. Gene
  3. LXN - latexin Gene

LXN - latexin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：乳胶蛋白

种属: Homo sapiens

同用名: ECI; TCI

基因 ID: 56925 | 基因类型: protein coding

关于 LXN

Cytogenetic location: 3q25.32 Genomic coordinates (GRCh38): 3:158,666,414-158,672,648 (from NCBI)

This gene has 2 transcripts (splice variants), 191 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 17.1), gall bladder (RPKM 15.4) and 24 other tissues.

功能概要

该基因编码唯一已知的锌依赖性金属羧肽酶蛋白抑制剂。编码的蛋白质乳胶下调造血干细胞的数量。由于启动子高甲基化，该蛋白质被发现在癌细胞中下调。[RefSeq 提供，2020 年 7 月]

This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in Cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020]

LXN 基因产物(1)

mRNA Protein Name
NM_020169.4 NP_064554.3 latexin
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LXN 蛋白结构

Latexin

Latexin: Latexin (2 - 220)

  • 0
  • 100
  • 200
  • 222 a.a.
蛋白主名 其他名称

latexin

MUM

LXN 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LXN Q9BS40 MAGEA8 Homo sapiens P43361
Y2H Array
25416956
种属内
LXN Q9BS40 MAGEA8 Homo sapiens P43361
Y2H Prey Pooling
25416956
种属内
LXN Q9BS40 DNAJC11 Homo sapiens Q9NVH1
Y2H Array
32296183
种属内
LXN Q9BS40 DNAJC11 Homo sapiens Q9NVH1
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 DNAJC11 Homo sapiens Q9NVH1
Validated Y2H
32296183
种属内
LXN Q9BS40 NSMF Homo sapiens Q6X4W1-2
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 NSMF Homo sapiens Q6X4W1-2
Y2H Array
32296183
种属内
LXN Q9BS40 YIF1B Homo sapiens Q5BJH7-5
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 YIF1B Homo sapiens Q5BJH7-5
Y2H Array
32296183
种属内
LXN Q9BS40 IGSF11 Homo sapiens Q5DX21-2
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 IGSF11 Homo sapiens Q5DX21-2
Y2H Array
32296183
种属内
LXN Q9BS40 BOC Homo sapiens Q96DN7
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 BOC Homo sapiens Q96DN7
Y2H Array
32296183
种属内
LXN Q9BS40 CA3 Homo sapiens P07451
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 CA3 Homo sapiens P07451
Y2H Array
32296183
种属内
LXN Q9BS40 ZNF430 Homo sapiens Q2NKJ9
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 ZNF430 Homo sapiens Q2NKJ9
Y2H Array
32296183
种属内
LXN Q9BS40 MCMDC2 Homo sapiens Q4G0Z9
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 MCMDC2 Homo sapiens Q4G0Z9
Y2H Array
32296183
种属内
LXN Q9BS40 TRAIP Homo sapiens Q9BWF2
Y2H Array
32296183
种属内
LXN Q9BS40 TRAIP Homo sapiens Q9BWF2
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 TRAIP Homo sapiens Q9BWF2
Validated Y2H
32296183
种属内
LXN Q9BS40 FCGR3A Homo sapiens A0A1W2PQB1
Y2H Array
32296183
种属内
LXN Q9BS40 FCGR3A Homo sapiens A0A1W2PQB1
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 COX6A1 Homo sapiens P12074
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 COX6A1 Homo sapiens P12074
Y2H Array
32296183
种属内
LXN Q9BS40 RNF4 Homo sapiens P78317
Y2H Array
32296183
种属内
LXN Q9BS40 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 PPP1R3C Homo sapiens Q9UQK1
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 PPP1R3C Homo sapiens Q9UQK1
Validated Y2H
32296183
种属内
LXN Q9BS40 PPP1R3C Homo sapiens Q9UQK1
Y2H Array
32296183
种属内
LXN Q9BS40 CYBC1 Homo sapiens Q9BQA9
Y2H Array
32296183
种属内
LXN Q9BS40 CYBC1 Homo sapiens Q9BQA9
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 TMEM14A Homo sapiens Q9Y6G1
Validated Y2H
25416956
种属内
LXN Q9BS40 ZKSCAN4 Homo sapiens Q969J2
Y2H Array
32296183
种属内
LXN Q9BS40 ZKSCAN4 Homo sapiens Q969J2
Y2H Prey Pooling
25416956
种属内
LXN Q9BS40 ZKSCAN4 Homo sapiens Q969J2
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 ZKSCAN4 Homo sapiens Q969J2
Y2H Array
25416956
种属内
LXN Q9BS40 DPYD Homo sapiens Q12882
Validated Y2H
25416956
种属内
LXN Q9BS40 SPAG7 Homo sapiens O75391
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 SPAG7 Homo sapiens O75391
Y2H Array
32296183
种属内
LXN Q9BS40 SHKBP1 Homo sapiens Q8TBC3
Y2H Array
32296183
种属内
LXN Q9BS40 SHKBP1 Homo sapiens Q8TBC3
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 TRIM39 Homo sapiens Q9HCM9
Validated Y2H
25416956
种属内
LXN Q9BS40 ZNF679 Homo sapiens Q8IYX0
Y2H Array
32296183
种属内
LXN Q9BS40 ZNF679 Homo sapiens Q8IYX0
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 ZCCHC17 Homo sapiens Q9NP64
Y2H Prey Pooling
32296183
种属内
LXN Q9BS40 ZCCHC17 Homo sapiens Q9NP64
Validated Y2H
32296183
种属内
LXN Q9BS40 ZCCHC17 Homo sapiens Q9NP64
Y2H Array
32296183
种属内
LXN Q9BS40 PAX6 Homo sapiens P26367
Y2H Array
32296183
种属内
LXN Q9BS40 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 LXN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73841 Latexin Protein, Human (His) Q9BS40/NP_064554.3 (E2-E222) ≥95%
HY-P73842 Latexin Protein, Human (HEK293, Fc) Q9BS40 (E2-E222) ≥95%

关联疾病

疾病名称 别名
Lissencephaly 7 With Cerebellar Hypoplasia

LIS7

Lissencephaly 7, With Cerebellar Hypoplasia

Lissencephaly, Type 7, With Cerebellar Hypoplasia
Lissencephaly 8

LIS8
Encephalitozoonosis

Infection By Encephalitozoon
Amyloidosis, Familial Visceral

Ostertag Type Amyloidosis

German Type Amyloidosis

Familial Renal Amyloidosis

Amyloidosis Viii

Amyloidosis, 3 Or More Types

Familial Visceral Amyloidosis

Familial Amyloid Nephropathy

Hereditary Amyloid Nephropathy

Amyloidosis, Familial Renal

Amyloidosis, Systemic Nonneuropathic

Amyloidosis Familial Visceral

Amyloidosis 8

Amyloidosis, Ostertag Type

Hereditary Amyloidosis With Primary Renal Involvement

Hereditary Renal Amyloidosis

Renal Amyloidosis

Amyloidosis, Renal

Systemic Nonneuropathic Amyloidosis

Amyloidosis Familial Renal

Amyloidosis Systemic Nonneuropathic

Hereditary Amyloidosis With Primary Renal Involement

AMYL8

Systemic Non-Neuropathic Amyloidosis

Amyloid Nephropathy
Comedo Carcinoma

Comedocarcinoma

High Grade Ductal Breast Carcinoma In Situ
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07895 LXN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus LXN VGNC VGNC:63332
Rattus norvegicus LXN RGD RGD:68361
Mus musculus LXN MGD MGI:107633
Macaca mulatta LXN VGNC VGNC:74279
Bos taurus LXN VGNC VGNC:31087
Canis familiaris LXN VGNC VGNC:42871
Others LXN NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z