PTPN4 - protein tyrosine phosphatase non-receptor type 4 Gene

中文名称：蛋白酪氨酸磷酸酶非受体 4 型

种属: Homo sapiens

同用名: MEG; PTPMEG; PTPMEG1

关于 PTPN4

功能概要

该基因编码的蛋白质是蛋白酪氨酸磷酸酶 (PTP) 家族的成员。已知 PTP 是调节多种细胞过程的信号分子，包括细胞生长、分化、有丝分裂周期和致癌转化。该蛋白包含一个 C 端 PTP 结构域和一个 N 端结构域，与细胞骨架相关蛋白的带 4.1 超家族同源。该 PTP 已被证明与谷氨酸受体 delta 2 和 epsilon 亚基相互作用，并且被认为通过酪氨酸去磷酸化在谷氨酸受体下游的信号传导中发挥作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the protein tyrosine Phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]