1. Gene
  2. INIP - INTS3 and NABP interacting protein Gene

INIP - INTS3 and NABP interacting protein Gene

中文名称:INTS3 和 NABP 相互作用蛋白

种属: Homo sapiens

同用名: MISE; SOSSC; SSBIP1; C9orf80; HSPC043; hSSBIP1

基因 ID: 58493 | 基因类型: protein coding

关于 INIP

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:112,683,926-112,718,117 (from NCBI)

This gene has 6 transcripts (splice variants) and 221 orthologues. Ubiquitous expression in lymph node (RPKM 8.2), colon (RPKM 6.8) and 25 other tissues.

功能概要

由该基因编码的蛋白质是单链 DNA 结合复合物的一个亚基,对维持基因组稳定性很重要。这些复合物参与 G2/M 检查点控制和同源重组修复。[RefSeq 提供,2016 年 7 月]

The protein encoded by this gene is a subunit of single-stranded DNA binding complexes that are important for maintaining genome stability. These complexes are involved in G2/M checkpoint control and homologous recombination repair. [provided by RefSeq, Jul 2016]

INIP 基因产物(7)

mRNA Protein Name
NM_001329585.2 NP_001316514.1 SOSS complex subunit C isoform b
NM_001329586.2 NP_001316515.1 SOSS complex subunit C isoform c
NM_001329587.2 NP_001316516.1 SOSS complex subunit C isoform d
NM_001329588.2 NP_001316517.1 SOSS complex subunit C isoform e
NM_001329589.2 NP_001316518.1 SOSS complex subunit C isoform e
NM_001329590.2 NP_001316519.1 SOSS complex subunit C isoform e
NM_021218.3 NP_067041.1 SOSS complex subunit C isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19683501 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IMP
IMP: 通过突变表型推断
19683501 GOA
involved in DNA repair IMP
IMP: 通过突变表型推断
19605351 GOA
involved in double-strand break repair via homologous recombination IDA
IDA: 通过直接分析推断
19683501 GOA
involved in mitotic G2/M transition checkpoint IDA
IDA: 通过直接分析推断
19683501 GOA
involved in response to ionizing radiation IMP
IMP: 通过突变表型推断
19605351 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SOSS complex IDA
IDA: 通过直接分析推断
18449195 GOA
part of SOSS complex IPI
IPI: 通过物理相互作用推断
19683501 GOA
located in nucleus IDA
IDA: 通过直接分析推断
19605351 GOA
located in site of double-strand break IDA
IDA: 通过直接分析推断
19683501 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

SOSS complex subunit C

SSB-interacting protein 1

INIP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
INIP Q9NRY2 KRT34 Homo sapiens O76011 32296183
种属内
INIP Q9NRY2 KRT34 Homo sapiens O76011 32296183
种属内
INIP Q9NRY2 INTS3 Homo sapiens Q68E01 19683501
种属内
INIP Q9NRY2 RBPMS Homo sapiens Q93062 25416956
种属内
INIP Q9NRY2 DGCR6L Homo sapiens Q9BY27 32296183
种属内
INIP Q9NRY2 ARID5A Homo sapiens Q03989 32296183
种属内
INIP Q9NRY2 ARID5A Homo sapiens Q03989 32296183
种属内
INIP Q9NRY2 BPIFA1 Homo sapiens Q9NP55 32296183
种属内
INIP Q9NRY2 BPIFA1 Homo sapiens Q9NP55 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Narcissistic Personality Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus INIP VGNC VGNC:102940
Rattus norvegicus INIP RGD RGD:1307983
Mus musculus INIP MGD MGI:1913459
Bos taurus INIP VGNC VGNC:30204
Canis familiaris INIP VGNC VGNC:49804