RABGGTB - Rab geranylgeranyltransferase subunit beta Gene

中文名称：Rab 香叶基香叶基转移酶 β 亚基

种属: Homo sapiens

同用名: GGTB

关于 RABGGTB

功能概要

该基因编码 Rab 香叶基香叶基转移酶 (RabGGTase) 的 β 亚基，该酶属于蛋白质异戊二烯基转移酶家族。 RabGGTase 催化翻译后将香叶基香叶基添加到 Rab GTP 酶的 C 末端半胱氨酸残基上。该基因的内含子区域存在三个小的核仁 RNA 基因。已经观察到该基因的交替剪接转录物变体。与该基因相关的假基因位于 3 号染色体上。[RefSeq 提供，2013 年 1 月]

This gene encodes the beta-subunit of the Enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]