1. Gene
  2. Cd14 - CD14 molecule Gene

Cd14 - CD14 molecule Gene

种属: Rattus norvegicus

基因 ID: 60350 | 基因类型: protein coding

关于 Cd14

功能概要

Predicted to enable Lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including cellular response to lipopolysaccharide; response to magnesium ion; and response to tumor necrosis factor. Located in cell surface; extracellular space; and plasma membrane. Used to study perinatal necrotizing enterocolitis. Biomarker of Hirschsprung's disease; cholestasis; obstructive jaundice; and periodontitis. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and pulmonary tuberculosis. Orthologous to human CD14 (CD14 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd14 基因产物(1)

mRNA Protein Name
NM_021744.1 NP_068512.1 monocyte differentiation antigen CD14 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18787027 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
22511970 RGD
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
12046090 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
19464360 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
10414605 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
16631199 RGD
involved in response to magnesium ion IEP
IEP: 通过表达模式推断
16180088 RGD
involved in response to tumor necrosis factor IMP
IMP: 通过突变表型推断
10777809 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
12046090 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
12835948 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

monocyte differentiation antigen CD14

CD14 antigen

myeloid cell-specific leucine-rich glycoprotein

重组 Cd14 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74331 CD14 Protein, Rat (HEK293, His) Q63691 (S18-Y341) ≥95%
HY-P74332 CD14 Protein, Rat (HEK293, Fc) Q63691 (M1-Y341) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd14 NCBI NCBI:929
Canis familiaris Cd14 NCBI NCBI:607076
Macaca fascicularis Cd14 NCBI NCBI:102129342
Mus musculus Cd14 NCBI NCBI:12475
Leporidae Cd14 NCBI
Macaca mulatta Cd14 NCBI NCBI:697482