RPS15A - ribosomal protein S15a Gene

中文名称：核糖体蛋白 S15a

种属: Homo sapiens

同用名: S15a; DBA20

基因 ID: 6210 | 基因类型: protein coding

关于 RPS15A

Cytogenetic location: 16p12.3 Genomic coordinates (GRCh38): 16:18,781,295-18,790,334 (from NCBI)

This gene has 13 transcripts (splice variants), 129 orthologues and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 1052.3), bone marrow (RPKM 811.7) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白 S8P 家族。它位于细胞质中。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS15A 基因产物(2)

mRNA	Protein	Name
NM_001019.5	NP_001010.2	40S ribosomal protein S15a
NM_001030009.2	NP_001025180.1	40S ribosomal protein S15a

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	24965446	GOA
enables structural constituent of ribosome	IDA IDA: 通过直接分析推断	23636399	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of cell cycle	IDA IDA: 通过直接分析推断	15108328	GOA
involved in positive regulation of cell population proliferation	IDA IDA: 通过直接分析推断	15108328	GOA
involved in response to virus	IDA IDA: 通过直接分析推断	15108328	GOA
involved in ribosomal small subunit biogenesis	IDA IDA: 通过直接分析推断	34516797	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	15108328	GOA
located in cytosolic ribosome	IDA IDA: 通过直接分析推断	23636399	GOA
part of cytosolic small ribosomal subunit	IDA IDA: 通过直接分析推断	8706699	GOA
part of small-subunit processome	IDA IDA: 通过直接分析推断	34516797	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RPS15A 蛋白结构

Ribosomal_S8

0
100
130 a.a.

蛋白主名

其他名称

40S ribosomal protein S15a

small ribosomal subunit protein uS8

RPS15A 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RPS15A	P62244	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
种属内	RPS15A	P62244	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
种属内	RPS15A	P62244	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
种属内	RPS15A	P62244	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
种属内	RPS15A	P62244	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
种属内	RPS15A	P62244	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
种属内	RPS15A	P62244	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
种属内	RPS15A	P62244	GSN	Homo sapiens	P06396	Validated Y2H	32814053
种属内	RPS15A	P62244	GSN	Homo sapiens	P06396	Y2H Array	32814053
种属内	RPS15A	P62244	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
种属内	RPS15A	P62244	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
种属内	RPS15A	P62244	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
种属内	RPS15A	P62244	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
种属内	RPS15A	P62244	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
种属内	RPS15A	P62244	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
种属内	RPS15A	P62244	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
种属内	RPS15A	P62244	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
种属内	RPS15A	P62244	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
种属内	RPS15A	P62244	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
种属内	RPS15A	P62244	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
种属内	RPS15A	P62244	WFS1	Homo sapiens	O76024	Y2H Array	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Diamond-Blackfan Anemia 20

DBA20

Rps15a-Related Diamond-Blackfan Anemia

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

Macrocytic Anemia

Anemia Macrocytic	Anemia, Macrocytic
Macrocytic Anaemia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12226	RPS15A Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	RPS15A	RGD	RGD:619939
Mus musculus	RPS15A	MGD	MGI:2389091

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RPS15A - ribosomal protein S15a Gene

关于 RPS15A

功能概要

RPS15A 基因产物(2)

RPS15A 蛋白结构

RPS15A 蛋白互作信息

关联疾病

直系同源

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RPS15A - ribosomal protein S15a Gene

关于 RPS15A

功能概要

RPS15A 基因产物(2)

RPS15A 蛋白结构

RPS15A 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z