1. Gene
  2. RPS25 - ribosomal protein S25 Gene

RPS25 - ribosomal protein S25 Gene

中文名称:核糖体蛋白 S25

种属: Homo sapiens

同用名: S25

基因 ID: 6230 | 基因类型: protein coding

关于 RPS25

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:119,015,717-119,018,343 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele and 201 orthologues. Ubiquitous expression in ovary (RPKM 1368.6), lymph node (RPKM 772.3) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器,由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白的 S25E 家族。它位于细胞质中。作为典型的编码核糖体蛋白的基因,该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供,2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS25 基因产物(1)

mRNA Protein Name
NM_001028.3 NP_001019.1 40S ribosomal protein S25
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22720776 GOA
enables structural constituent of ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
enables structural constituent of ribosome IMP
IMP: 通过突变表型推断
18697920 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in rRNA processing IMP
IMP: 通过突变表型推断
18697920 GOA
involved in ribosomal small subunit biogenesis IMP
IMP: 通过突变表型推断
18697920 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosolic ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
part of cytosolic small ribosomal subunit IDA
IDA: 通过直接分析推断
8706699 GOA
located in nucleolus IDA
IDA: 通过直接分析推断
10050887 GOA
located in nucleus IDA
IDA: 通过直接分析推断
22720776 GOA
is active in postsynaptic density EXP
EXP: 通过实验结果推断
21170055 GOA
is active in postsynaptic density IDA
IDA: 通过直接分析推断
21170055 GOA
located in ribosome IDA
IDA: 通过直接分析推断
1748303 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RPS25 蛋白结构

Ribosomal_S25

Ribosomal_S25: S25 ribosomal protein (1 - 113)

  • 0
  • 100
  • 125 a.a.
蛋白主名 其他名称

40S ribosomal protein S25

small ribosomal subunit protein eS25

关联疾病

疾病名称 别名
Chromosome 5q Deletion Syndrome

5q- Syndrome

Mar

Myelodysplastic Syndrome Associated With Isolated Del Chromosome Abnormality

Macrocytic Anemia, Refractory, Due To 5q Deletion, Somatic

5q Deletion Syndrome

5q Minus Syndrome

Refractory Macrocytic Anemia Due To 5q Deletion

Myelodysplastic Syndrome With Isolated Del

Macrocytic Anemia, Refractory, Due To 5q Deletion

5q- Syndrome, Refractory Macrocytic Anemia Due To 5q Deletion

5q Syndrome

Chromosome 5q Deletion

Myelodysplastic Syndrome With 5q Deletion

Myelodysplastic Syndrome With 5q Deletion Syndrome

Anemia, Macrocytic, Refractory, Due To 5q Deletion, Somatic

5q-Syndrome

Chromosome 5, Trisomy 5q

Loss Of Chromosome 5q

5 Q- Syndrome

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RPS25 RGD RGD:621043
Mus musculus RPS25 MGD MGI:1922867