S100A11 - S100 calcium binding protein A11 Gene

中文名称：S100 钙结合蛋白 A11

种属: Homo sapiens

同用名: MLN70; S100C; HEL-S-43

关于 S100A11

功能概要

由该基因编码的蛋白质是包含 2 个 EF 手钙结合基序的 S100 蛋白质家族的成员。 S100 蛋白定位于多种细胞的细胞质和/或细胞核，并参与许多细胞过程的调节，例如细胞周期进程和分化。 S100 基因包括至少 13 个成员，它们成簇地位于染色体 1q21 上。这种蛋白质可能在运动、侵袭和微管蛋白聚合中发挥作用。该基因的染色体重排和表达改变与肿瘤转移有关。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008]