1. Gene
  2. Mertk - MER proto-oncogene, tyrosine kinase Gene

Mertk - MER proto-oncogene, tyrosine kinase Gene

种属: Rattus norvegicus

同用名: rdy

基因 ID: 65037 | 基因类型: protein coding

关于 Mertk

功能概要

Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in phagocytosis; positive regulation of phagocytosis; and protein phosphorylation. Located in photoreceptor outer segment. Used to study retinal degeneration. Human ortholog(s) of this gene implicated in retinitis pigmentosa 38. Orthologous to human MERTK (Mer proto-oncogene, tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mertk 基因产物(1)

mRNA Protein Name
NM_022943.1 NP_075232.1 tyrosine-protein kinase Mer precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in phagocytosis IDA
IDA: 通过直接分析推断
11861639 RGD
involved in phagocytosis IMP
IMP: 通过突变表型推断
11861639 RGD
involved in positive regulation of phagocytosis IDA
IDA: 通过直接分析推断
11592982 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
11861639 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
11861639 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tyrosine-protein kinase Mer

Receptor tyrosine tinase gene probably the gene for Rdy

c-mer proto-oncogene tyrosine kinase

proto-oncogene c-Mer

proto-oncogene tyrosine-protein kinase MER

receptor tyrosine kinase MerTK

retinal dystrophy

重组 Mertk 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700594 MERTK Protein, Rat (HEK293, His) P57097 (G19-M497) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mertk NCBI NCBI:10461
Macaca fascicularis Mertk NCBI NCBI:102143798
Mus musculus Mertk NCBI NCBI:17289