2. Gene
  3. Nherf2 - NHERF family PDZ scaffold protein 2 Gene

Nherf2 - NHERF family PDZ scaffold protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sip1; Octs2; Sip-1; Tka-1; E3karp; Sryip1; NHERF-2; Slc9a3r2; 0610011L07Rik; 1200011K07Rik; 2010007A20Rik

基因 ID: 65962 | 基因类型: protein coding

关于 Nherf2

功能概要

Enables Phosphatase binding activity. Acts upstream of or within negative regulation of phosphatidylinositol 3-kinase signaling and sensory perception of sound. Located in several cellular components, including apical plasma membrane; nucleus; and stereocilium. Is expressed in cochlea epithelium and organ of Corti. Orthologous to human SLC9A3R2 (SLC9A3 regulator 2). [provided by Alliance of Genome Resources, Apr 2022]

Nherf2 基因产物(3)

mRNA Protein Name
NM_001357796.1 NP_001344725.1 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform C
NM_023055.2 NP_075542.2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform A
NM_023449.3 NP_075938.2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatase binding IPI
IPI: 通过物理相互作用推断
16456542 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10410901 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IGI
IGI: 通过遗传相互作用推断
16456542 MGI
acts upstream of phosphatidylinositol 3-kinase/protein kinase B signal transduction IGI
IGI: 通过遗传相互作用推断
16456542 MGI
acts upstream of or within sensory perception of sound IMP
IMP: 通过突变表型推断
24920589 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
12169661 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10410901 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10410901 MGI
located in stereocilium IDA
IDA: 通过直接分析推断
24920589 MGI
located in stereocilium bundle IDA
IDA: 通过直接分析推断
24920589 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Na(+)/H(+) exchange regulatory cofactor NHE-RF2

NHE3 kinase A regulatory protein E3KARP

SRY-interacting protein 1

sodium-hydrogen exchanger regulatory factor 2

solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

tyrosine kinase activator protein 1

Nherf2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Nherf2 Q9JHL1 Pten Mus musculus O08586
Pull Down
16456542
种属内
Nherf2 Q9JHL1 Pdgfrb Mus musculus P05622
Chromatography
16456542
种属内
Nherf2 Q9JHL1 Pdgfrb Mus musculus P05622
Pull Down
16456542
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09283 NHERF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nherf2 NCBI NCBI:9351
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