1. Gene
  2. Lrfn2 - leucine rich repeat and fibronectin type III domain containing 2 Gene

Lrfn2 - leucine rich repeat and fibronectin type III domain containing 2 Gene

种属: Mus musculus

同用名: SALM1; mKIAA1246; 5730420O05Rik

基因 ID: 70530 | 基因类型: protein coding

关于 Lrfn2

功能概要

Involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Located in Schaffer collateral - CA1 synapse and cell surface. Is expressed in several structures, including central nervous system; esophagus; eye; male reproductive gland or organ; and trigeminal nerve. Used to study autism spectrum disorder. Orthologous to human LRFN2 (leucine rich repeat and fibronectin type III domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Lrfn2 基因产物(1)

mRNA Protein Name
NM_027452.3 NP_081728.2 leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16495444 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
28604739 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
28604739 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
28604739 MGI
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
28604739 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
28604739 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
28604739 MGI
located in cell surface IDA
IDA: 通过直接分析推断
16828986 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
31368584 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
31368584 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat and fibronectin type-III domain-containing protein 2

Lrfn2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Lrfn2 Q80TG9 Dlg4 Mus musculus Q62108 28604739
种属内
Lrfn2 Q80TG9 Dlg4 Mus musculus Q62108 16495444
种属内
Lrfn2 Q80TG9 Dlg1 Mus musculus Q811D0 16495444
种属内
Lrfn2 Q80TG9 Dlg1 Mus musculus Q811D0 16495444
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrfn2 NCBI NCBI:57497