1. Gene
  2. Tradd - TNFRSF1A-associated via death domain Gene

Tradd - TNFRSF1A-associated via death domain Gene

种属: Mus musculus

同用名: 9130005N23Rik

基因 ID: 71609 | 基因类型: protein coding

关于 Tradd

功能概要

Predicted to enable death domain binding activity; identical protein binding activity; and signaling receptor binding activity. Involved in positive regulation of hair follicle development. Acts upstream of or within extrinsic apoptotic signaling pathway. Located in cytoplasm. Is expressed in adrenal gland; genitourinary system; liver; lung; and spleen. Orthologous to human TRADD (TNFRSF1A associated via death domain). [provided by Alliance of Genome Resources, Apr 2022]

Tradd 基因产物(1)

mRNA Protein Name
NM_001033161.2 NP_001028333.1 tumor necrosis factor receptor type 1-associated DEATH domain protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16702408 MGI
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
8565075 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within extrinsic apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
22089168 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
18641653 MGI
involved in positive regulation of hair follicle development IMP
IMP: 通过突变表型推断
16702408 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16702408 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor type 1-associated DEATH domain protein

TNF receptor 1 associated signal transducer

TNFR1-associated DEATH domain protein

Tradd 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Tradd Q3U0V2 Tlr4 Mus musculus Q9QUK6
Anti Bait CoIP
18719121
种属内
Tradd Q3U0V2 Ripk1 Mus musculus Q60855
Anti Bait CoIP
18719121
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tradd NCBI NCBI:8717