2. Gene
  3. Arhgef6 - Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 Gene

Arhgef6 - Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: alpha-PIX; 1600028C08Rik; 1700038J06Rik; 4930592P22Rik

基因 ID: 73341 | 基因类型: protein coding

关于 Arhgef6

功能概要

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in lamellipodium assembly. Located in cell-cell junction and lamellipodium. Is expressed in somite and unsegmented mesenchyme. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 46. Orthologous to human ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef6 基因产物(11)

mRNA Protein Name
NM_001358573.2 NP_001345502.1 rho guanine nucleotide exchange factor 6 isoform 2
NM_001405168.1 NP_001392097.1 rho guanine nucleotide exchange factor 6 isoform 2
NM_001405169.1 NP_001392098.1 rho guanine nucleotide exchange factor 6 isoform 2
NM_001405170.1 NP_001392099.1 rho guanine nucleotide exchange factor 6 isoform 3
NM_001405171.1 NP_001392100.1 rho guanine nucleotide exchange factor 6 isoform 4
NM_001405172.1 NP_001392101.1 rho guanine nucleotide exchange factor 6 isoform 4
NM_001405173.1 NP_001392102.1 rho guanine nucleotide exchange factor 6 isoform 5
NM_001405174.1 NP_001392103.1 rho guanine nucleotide exchange factor 6 isoform 6
NM_001405175.1 NP_001392104.1 rho guanine nucleotide exchange factor 6 isoform 7
NM_001405176.1 NP_001392105.1 rho guanine nucleotide exchange factor 6 isoform 8
NM_152801.3 NP_690014.3 rho guanine nucleotide exchange factor 6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18325335 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lamellipodium assembly IMP
IMP: 通过突变表型推断
18325335 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
18325335 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rho guanine nucleotide exchange factor 6

Rac/Cdc42 guanine exchange factor (GEF) 6

alpha PIX Rho GTPase guanine nucleotide exchange factor

rac/Cdc42 guanine nucleotide exchange factor 6

Arhgef6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Arhgef6 Q8K4I3 PARVB Homo sapiens Q9HBI1
Anti Bait CoIP
18325335
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00963 ARHGEF6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arhgef6 NCBI NCBI:9459
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