TMEM50B - transmembrane protein 50B Gene

中文名称：跨膜蛋白 50B

种属: Homo sapiens

同用名: C21orf4; HCVP7TP3

基因 ID: 757 | 基因类型: protein coding

关于 TMEM50B

Cytogenetic location: 21q22.11 Genomic coordinates (GRCh38): 21:33,432,486-33,479,974 (from NCBI)

This gene has 10 transcripts (splice variants), 1 gene allele, 175 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 53.6), gall bladder (RPKM 21.3) and 24 other tissues.

功能概要

预计通过多泡体分选途径参与晚期内体到液泡的运输。位于内质网。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TMEM50B 基因产物(1)

mRNA	Protein	Name
NM_006134.7	NP_006125.2	transmembrane protein 50B

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TMEM50B 蛋白结构

UPF0220

0
100
158 a.a.

蛋白主名

其他名称

transmembrane protein 50B

HCV p7-trans-regulated protein 3

TMEM50B 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TMEM50B	P56557	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	GPX8	Homo sapiens	Q8TED1	Validated Y2H	32296183
种属内	TMEM50B	P56557	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
种属内	TMEM50B	P56557	FXYD3	Homo sapiens	Q14802-3	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	FXYD3	Homo sapiens	Q14802-3	Y2H Array	32296183
种属内	TMEM50B	P56557	FXYD3	Homo sapiens	Q14802-3	Validated Y2H	32296183
种属内	TMEM50B	P56557	SLC16A13	Homo sapiens	Q7RTY0	Validated Y2H	32296183
种属内	TMEM50B	P56557	SLC16A13	Homo sapiens	Q7RTY0	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	SLC16A13	Homo sapiens	Q7RTY0	Y2H Array	32296183
种属内	TMEM50B	P56557	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	GPR152	Homo sapiens	Q8TDT2	Validated Y2H	32296183
种属内	TMEM50B	P56557	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
种属内	TMEM50B	P56557	LEPROT	Homo sapiens	O15243	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	TMEM88	Homo sapiens	Q6PEY1	Y2H Array	32296183
种属内	TMEM50B	P56557	TMEM88	Homo sapiens	Q6PEY1	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	TMEM88	Homo sapiens	Q6PEY1	Validated Y2H	32296183
种属内	TMEM50B	P56557	SCN3B	Homo sapiens	Q9NY72	Validated Y2H	32296183
种属内	TMEM50B	P56557	SCN3B	Homo sapiens	Q9NY72	Y2H Array	32296183
种属内	TMEM50B	P56557	SCN3B	Homo sapiens	Q9NY72	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	CLRN1	Homo sapiens	P58418	Y2H Array	32296183
种属内	TMEM50B	P56557	CLRN1	Homo sapiens	P58418	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	CLRN1	Homo sapiens	P58418	Validated Y2H	32296183
种属内	TMEM50B	P56557	SLC35C2	Homo sapiens	Q9NQQ7-3	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	SLC35C2	Homo sapiens	Q9NQQ7-3	Y2H Array	32296183
种属内	TMEM50B	P56557	SLC35C2	Homo sapiens	Q9NQQ7-3	Validated Y2H	32296183
种属内	TMEM50B	P56557	HLA-DPA1	Homo sapiens	Q95HB9	Validated Y2H	32296183
种属内	TMEM50B	P56557	HLA-DPA1	Homo sapiens	Q95HB9	Y2H Array	32296183
种属内	TMEM50B	P56557	HLA-DPA1	Homo sapiens	Q95HB9	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	SLC10A6	Homo sapiens	Q3KNW5	Validated Y2H	32296183
种属内	TMEM50B	P56557	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	SLC10A6	Homo sapiens	Q3KNW5	Y2H Array	32296183
种属内	TMEM50B	P56557	TMEM52B	Homo sapiens	Q4KMG9	Validated Y2H	32296183
种属内	TMEM50B	P56557	TMEM52B	Homo sapiens	Q4KMG9	Y2H Array	32296183
种属内	TMEM50B	P56557	TMEM52B	Homo sapiens	Q4KMG9	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	FAM209A	Homo sapiens	Q5JX71	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	FAM209A	Homo sapiens	Q5JX71	Y2H Array	32296183
种属内	TMEM50B	P56557	FAM209A	Homo sapiens	Q5JX71	Validated Y2H	32296183
种属内	TMEM50B	P56557	AMIGO1	Homo sapiens	Q86WK6	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	AMIGO1	Homo sapiens	Q86WK6	Y2H Array	32296183
种属内	TMEM50B	P56557	AMIGO1	Homo sapiens	Q86WK6	Validated Y2H	32296183
种属内	TMEM50B	P56557	NCR1	Homo sapiens	O76036-6	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	NCR1	Homo sapiens	O76036-6	Y2H Array	32296183
种属内	TMEM50B	P56557	LHFPL5	Homo sapiens	Q8TAF8	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	LHFPL5	Homo sapiens	Q8TAF8	Validated Y2H	32296183
种属内	TMEM50B	P56557	LHFPL5	Homo sapiens	Q8TAF8	Y2H Array	32296183
种属内	TMEM50B	P56557	EDA	Homo sapiens	Q92838	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	EDA	Homo sapiens	Q92838	Validated Y2H	32296183
种属内	TMEM50B	P56557	EDA	Homo sapiens	Q92838	Y2H Array	32296183
种属内	TMEM50B	P56557	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
种属内	TMEM50B	P56557	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
种属内	TMEM50B	P56557	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	CREB3L1	Homo sapiens	Q96BA8	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	CREB3L1	Homo sapiens	Q96BA8	Validated Y2H	32296183
种属内	TMEM50B	P56557	CREB3L1	Homo sapiens	Q96BA8	Y2H Array	32296183
种属内	TMEM50B	P56557	BCL2L1	Homo sapiens	Q07817	Validated Y2H	32296183
种属内	TMEM50B	P56557	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
种属内	TMEM50B	P56557	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
种属内	TMEM50B	P56557	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Immunodeficiency 28

IMD28	Ifngr2 Deficiency
Immunodeficiency 28, Mycobacteriosis, Autosomal Recessive	Immunodeficiency 28, Mycobacteriosis
Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Ifngammar2 Deficiency	Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interferon Gamma Receptor 2 Deficiency
Msmd Due To Complete Ifngammar2 Deficiency	Msmd Due To Complete Interferon Gamma Receptor 2 Deficiency
Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar2 Deficiency	Autosomal Recessive Msmd Due To Partial Ifngammar2 Deficiency
Autosomal Recessive Msmd Due To Partial Interferon Gamma Receptor 2 Deficiency	Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 2 Deficiency
Immunodeficiency, Type 28, Mycobacteriosis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14729	TMEM50B Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	TMEM50B	RGD	RGD:1307561
Felis catus	TMEM50B	VGNC	VGNC:66350
Bos taurus	TMEM50B	VGNC	VGNC:36093
Macaca mulatta	TMEM50B	VGNC	VGNC:84756
Mus musculus	TMEM50B	MGD	MGI:1925225

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TMEM50B - transmembrane protein 50B Gene

关于 TMEM50B

功能概要

TMEM50B 基因产物(1)

TMEM50B 蛋白结构

TMEM50B 蛋白互作信息

关联疾病

直系同源

热门区域

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TMEM50B - transmembrane protein 50B Gene

关于 TMEM50B

功能概要

TMEM50B 基因产物(1)

TMEM50B 蛋白结构

TMEM50B 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z