2. Gene
  3. SLC30A1 - solute carrier family 30 member 1 Gene

SLC30A1 - solute carrier family 30 member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 30 成员 1

种属: Homo sapiens

同用名: ZNT1; ZRC1

基因 ID: 7779 | 基因类型: protein coding

关于 SLC30A1

Cytogenetic location: 1q32.3 Genomic coordinates (GRCh38): 1:211,571,568-211,579,161 (from NCBI)

This gene has 1 transcript (splice variant), 221 orthologues and 8 paralogues. Ubiquitous expression in liver (RPKM 22.8), duodenum (RPKM 15.1) and 25 other tissues.

功能概要

预计可启用钙通道抑制剂活性和锌离子跨膜转运蛋白活性。预计参与多个过程，包括细胞二价无机阳离子稳态；无机阳离子跨膜转运；和运输的负面监管。预计在子宫内胚胎发育的上游或内部起作用。位于多种细胞成分中，包括高尔基体；内质网；和核膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Calcium Channel Inhibitor activity and zinc ion transmembrane transporter activity. Predicted to be involved in several processes, including cellular divalent inorganic cation homeostasis; inorganic cation transmembrane transport; and negative regulation of transport. Predicted to act upstream of or within in utero embryonic development. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and nuclear membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC30A1 基因产物(1)

mRNA Protein Name
NM_021194.3 NP_067017.2 zinc transporter 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18158319 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in defense response to bacterium IDA
IDA: 通过直接分析推断
32441444 GOA
involved in intracellular zinc ion homeostasis IDA
IDA: 通过直接分析推断
18158319 GOA
involved in zinc ion import into organelle IDA
IDA: 通过直接分析推断
32441444 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
18158319 GOA
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
31471319 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
18158319 GOA
located in cytoplasmic vesicle membrane IDA
IDA: 通过直接分析推断
32441444 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
18158319 GOA
located in nuclear membrane IDA
IDA: 通过直接分析推断
18158319 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
17349999 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC30A1 蛋白结构

Cation_efflux

Cation_efflux: Cation efflux family (11 - 423)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 507 a.a.
蛋白主名 其他名称

zinc transporter 1

solute carrier family 30 (zinc transporter), member 1

SLC30A1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SLC30A1 Q9Y6M5 SLC30A2 Homo sapiens Q9BRI3
BiFC
25657003
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Epidermodysplasia Verruciformis 1

Epidermodysplasia Verruciformis

Epidermodysplasia Verruciformis, Susceptibility To, 1

Lutz-Lewandowsky Epidermodysplasia Verruciformis

EV1

Lewandowsky-Lutz Syndrome

Ev
Acrodermatitis Enteropathica, Zinc-Deficiency Type

Acrodermatitis Enteropathica

AEZ

Enteropathica

Brandt Syndrome

Ae

Acrodermatitis Enteropathica Zinc Deficiency Type

Danbolt-Cross Syndrome

Acrodermatitis Enteropathica, Zinc Deficiency Type

Inherited Zinc Deficiency

Acrodermatitis Enteropathica, Zinc Deficiency

Danbolt-Closs Syndrome

Primary Zinc Malabsorption Syndrome
Ehlers-Danlos Syndrome, Spondylodysplastic Type, 3

Spondylocheirodysplasia, Ehlers-Danlos Syndrome-Like

Scd-Eds

EDSSPD3

Ehlers-Danlos Syndrome Spondylodysplastic Type 3

Ehlers-Danlos Syndrome, Spondylocheirodysplastic Type

Slc39a13-Related Spondylodysplastic Ehlers-Danlos Syndrome

Slc39a13-Related Speds

Slc39a13-Related Spondylodysplastic Eds

Spondylocheirodysplastic Ehlers-Danlos Syndrome

Speds-Slc39a13

Ehlers-Danlos Syndrome-Like Spondylocheirodysplasia

Ehlers-Danlos Syndrome, Spondylodysplastic, Type 3
Superficial Mycosis

Piedra

Steroid-Modified Tinea Infection
Menkes Disease

Copper Transport Disease

Menkes Syndrome

MNK

Kinky Hair Disease

Steely Hair Disease

Menkes Kinky-Hair Syndrome

Mk

Steely Hair Syndrome

Menkea Syndrome

Md

Menkes Kinky Hair Syndrome

Hypocupremia, Congenital

Kinky Hair Syndrome

X-Linked Copper Deficiency

Menkes Kinky Hair Disease
Deficiency Anemia

Anemia

Deficiency Anemias

Anaemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13178 SLC30A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SLC30A1 VGNC VGNC:46346
Mus musculus SLC30A1 MGD MGI:1345281
Rattus norvegicus SLC30A1 RGD RGD:61918
Bos taurus SLC30A1 VGNC VGNC:34805
Felis catus SLC30A1 VGNC VGNC:107941
Macaca mulatta SLC30A1 VGNC VGNC:77451
Others SLC30A1 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z