ZXDC - ZXD family zinc finger C Gene

中文名称：ZXD 系列锌指 C

种属: Homo sapiens

同用名: ZXDL

基因 ID: 79364 | 基因类型: protein coding

关于 ZXDC

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:126,437,601-126,475,891 (from NCBI)

This gene has 4 transcripts (splice variants), 306 orthologues and 14 paralogues. Ubiquitous expression in bone marrow (RPKM 13.7), spleen (RPKM 5.6) and 25 other tissues.

功能概要

启用 C2H2 锌指结构域结合活性； LRR 域绑定活动；和转录共激活因子活性。参与转录的正调控，以 DNA 为模板。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Enables C2H2 zinc finger domain binding activity; LRR domain binding activity; and transcription coactivator activity. Involved in positive regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZXDC 基因产物(2)

mRNA	Protein	Name
NM_001040653.4	NP_001035743.1	zinc finger protein ZXDC isoform 2
NM_025112.5	NP_079388.3	zinc finger protein ZXDC isoform 1

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables C2H2 zinc finger domain binding	IPI IPI: 通过物理相互作用推断	17493635	GOA
enables LRR domain binding	IPI IPI: 通过物理相互作用推断	16600381	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	16600381	GOA
enables transcription coactivator activity	IMP IMP: 通过突变表型推断	17493635	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of DNA-templated transcription	IDA IDA: 通过直接分析推断	17696781	GOA
involved in positive regulation of DNA-templated transcription	IMP IMP: 通过突变表型推断	16600381	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZXDC 蛋白结构

zf-C2H2_4

zf-C2H2

zf-H2C2_2

zf-C2H2

zf-C2H2_4

0
200
400
600
800
858 a.a.

蛋白主名

其他名称

zinc finger protein ZXDC

SERH2790

ZXDC 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	ZXDC	Q2QGD7	CBR4	Homo sapiens	Q8N4T8	Validated Y2H	32296183
Intra	ZXDC	Q2QGD7	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	CIITA	Homo sapiens	P33076	Anti Bait CoIP	17493635
Intra	ZXDC	Q2QGD7	ZXDA	Homo sapiens	P98168	Anti Bait CoIP	17493635
Intra	ZXDC	Q2QGD7	MEPE	Homo sapiens	Q9NQ76	Validated Y2H	32296183
Intra	ZXDC	Q2QGD7	PSEN2	Homo sapiens	P49810	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	PSEN2	Homo sapiens	P49810	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	PSEN2	Homo sapiens	P49810	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	RNF11	Homo sapiens	Q9Y3C5	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	RNF11	Homo sapiens	Q9Y3C5	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	RNF11	Homo sapiens	Q9Y3C5	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	TTR	Homo sapiens	P02766	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	TTR	Homo sapiens	P02766	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	TTR	Homo sapiens	P02766	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	ZMYND19	Homo sapiens	Q96E35	Validated Y2H	32296183
Intra	ZXDC	Q2QGD7	PRPS1	Homo sapiens	P60891	Validated Y2H	32814053
Intra	ZXDC	Q2QGD7	PRPS1	Homo sapiens	P60891	Y2H Array	32814053
Intra	ZXDC	Q2QGD7	PRPS1	Homo sapiens	P60891	Y2H Pooling	32814053
Intra	ZXDC	Q2QGD7	ATXN1	Homo sapiens	P54253	Y2H Prey Pooling	23275563

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Microcephalic Osteodysplastic Primordial Dwarfism, Type Ii

Microcephalic Osteodysplastic Primordial Dwarfism Type Ii	Majewski Osteodysplastic Primordial Dwarfism Type Ii
MOPD2	Mopd Ii
Osteodysplastic Primordial Dwarfism Type Ii	Mopdii
Osteodysplastic Primordial Dwarfism Type 2	Osteodysplastic Primordial Dwarfism, Type Ii
Pcnt-Related Microcephalic Osteodysplastic Primordial Dwarfism	Microcephalic Osteodysplastic Primordial Dwarfism Type 2
Mopd 2	Microcephalic Osteodysplastic Primordial Dwarfism With Tooth Abnormalities
Mopd Type Ii	Microcephalic Osteodysplastic Primordial Dwarfism 2
Dwarfism, Primordial, Osteodysplastic, Microcephalic Type Ii

Moyamoya Disease 1

Moyamoya Disease	Spontaneous Occlusion Of The Circle Of Willis
Mymy	Progressive Intracranial Arterial Occlusion
Moyamoya Syndrome	MYMY1
Cerebrovascular Moyamoya Disease	Moya-Moya Disease
Progressive Intracranial Occlusive Arteropathy	Idiopathic Moyamoya Disease

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS16213	ZXDC Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	ZXDC	VGNC	VGNC:82559
Bos taurus	ZXDC	VGNC	VGNC:37392
Canis familiaris	ZXDC	VGNC	VGNC:48867
Felis catus	ZXDC	VGNC	VGNC:67391
Rattus norvegicus	ZXDC	RGD	RGD:1561296
Mus musculus	ZXDC	MGD	MGI:1933108

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ZXDC - ZXD family zinc finger C Gene

关于 ZXDC

功能概要

ZXDC 基因产物(2)

ZXDC 蛋白结构

ZXDC 蛋白互作信息

关联疾病

直系同源

热门区域

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ZXDC - ZXD family zinc finger C Gene

关于 ZXDC

功能概要

ZXDC 基因产物(2)

ZXDC 蛋白结构

ZXDC 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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F

G

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J

L

N

Q

S

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