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  2. SYNDIG1 - synapse differentiation inducing 1 Gene

SYNDIG1 - synapse differentiation inducing 1 Gene

中文名称:突触分化诱导 1

种属: Homo sapiens

同用名: DSPC2; IFITMD5; TMEM90B; C20orf39

基因 ID: 79953 | 基因类型: protein coding

关于 SYNDIG1

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:24,469,629-24,666,616 (from NCBI)

This gene has 2 transcripts (splice variants), 192 orthologues and 3 paralogues. Biased expression in brain (RPKM 1.9), heart (RPKM 1.6) and 11 other tissues.

功能概要

该基因编码的蛋白质属于干扰素诱导的跨膜蛋白质家族。大鼠中的一种类似蛋白质被认为可以调节兴奋性突触的发育。[RefSeq 提供,2013 年 7 月]

This gene encodes a protein that belongs to the interferon-induced transmembrane family of proteins. A similar protein in rat is thought to regulate the development of excitatory synapses. [provided by RefSeq, Jul 2013]

SYNDIG1 基因产物(3)

mRNA Protein Name
NM_001323606.2 NP_001310535.1 synapse differentiation-inducing gene protein 1
NM_001323607.2 NP_001310536.1 synapse differentiation-inducing gene protein 1
NM_024893.3 NP_079169.1 synapse differentiation-inducing gene protein 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
20152115 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SYNDIG1 蛋白结构

CD225

CD225: Interferon-induced transmembrane protein (177 - 244)

  • 0
  • 100
  • 200
  • 258 a.a.
蛋白主名 其他名称

synapse differentiation-inducing gene protein 1

dispanin subfamily C member 2

SYNDIG1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SYNDIG1 Q9H7V2 SLC16A13 Homo sapiens Q7RTY0
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 SLC16A13 Homo sapiens Q7RTY0
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 GPRC5D Homo sapiens Q9NZD1
Validated Y2H
32296183
Intra SYNDIG1 Q9H7V2 SLC35C2 Homo sapiens Q9NQQ7-3
Validated Y2H
32296183
Intra SYNDIG1 Q9H7V2 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra SYNDIG1 Q9H7V2 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Intra SYNDIG1 Q9H7V2 FATE1 Homo sapiens Q969F0
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Osteogenesis Imperfecta, Type V

Osteogenesis Imperfecta Type 5

OI5

Osteogenesis Imperfecta Type V

Oi Type 5

Oi Type V

Oi, Type V

Oi With Calcification In Interosseous Membranes

Type V Oi

Osteogenesis Imperfecta 5

Oi-V

Gliofibroma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SYNDIG1 VGNC VGNC:35519
Macaca mulatta SYNDIG1 VGNC VGNC:78130
Rattus norvegicus SYNDIG1 RGD RGD:1310753
Felis catus SYNDIG1 VGNC VGNC:81233
Canis familiaris SYNDIG1 VGNC VGNC:47025
Mus musculus SYNDIG1 MGD MGI:3702158