2. Gene
  3. LY6G6C - lymphocyte antigen 6 family member G6C Gene

LY6G6C - lymphocyte antigen 6 family member G6C Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：淋巴细胞抗原 6 家族成员 G6C

种属: Homo sapiens

同用名: G6c; NG24; C6orf24

基因 ID: 80740 | 基因类型: protein coding

关于 LY6G6C

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,718,648-31,721,746 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele and 91 orthologues. Restricted expression toward skin (RPKM 160.9).

功能概要

LY6G6C 属于白细胞抗原 6 (LY6) 基因簇，位于 6 号染色体上的主要组织相容性复合体 (MHC) III 类区域。LY6 超家族的成员通常包含 70 至 80 个氨基酸，包括 8 至 10 个半胱氨酸。大多数 LY6 蛋白通过直接参与信号转导的糖基磷脂酰肌醇 (GPI) 锚附着在细胞表面 (Mallya 等人，2002 [PubMed 12079290]) 。[OMIM 提供，2008 年 3 月]

LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 Amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]

LY6G6C 基因产物(1)

mRNA Protein Name
NM_025261.3 NP_079537.1 lymphocyte antigen 6 complex locus protein G6c precursor
蛋白主名 其他名称

lymphocyte antigen 6 complex locus protein G6c

lymphocyte antigen 6 complex, locus G6C

LY6G6C 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra LY6G6C O95867 SLC41A2 Homo sapiens Q96JW4
Validated Y2H
32296183
Intra LY6G6C O95867 SLC38A7 Homo sapiens Q9NVC3
Validated Y2H
32296183
Intra LY6G6C O95867 C4orf3 Homo sapiens Q8WVX3-2
Validated Y2H
32296183
Intra LY6G6C O95867 TMEM203 Homo sapiens Q969S6
Validated Y2H
32296183
Intra LY6G6C O95867 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
Intra LY6G6C O95867 YIPF6 Homo sapiens Q96EC8
Validated Y2H
32296183
Intra LY6G6C O95867 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Lynch Syndrome I

Lynch Syndrome 1

Colorectal Cancer, Hereditary Nonpolyposis, Type 1

HNPCC1

Fcc1

Lynch Syndrome Ii

Colon Cancer, Familial Nonpolyposis, Type 1

Coca1

Familial Nonpolyposis Colon Cancer Type 1

Hereditary Nonpolyposis Colorectal Cancer Type 1

Hereditary Non-Polyposis Colorectal Cancer 1

Hereditary Non-Polyposis Colorectal Cancer 3

Hnpcc3

Lynch Cancer Family Syndrome

Lynch Syndrome

Lynch Syndrome Type I

Lynch Syndrome Type Ii

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 1

Hereditary Nonpolyposis Colorectal Cancer

Colorectal Cancer, Hereditary Nonpolyposis, Type 3

Hereditary Non-Polyposis Colon Cancer Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07898 LY6G6C Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus LY6G6C VGNC VGNC:63334
Mus musculus LY6G6C MGD MGI:2148930
Rattus norvegicus LY6G6C RGD RGD:1302999
Macaca mulatta LY6G6C VGNC VGNC:74285
Bos taurus LY6G6C VGNC VGNC:31090
Canis familiaris LY6G6C VGNC VGNC:42875
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