1. Gene
  2. SLC38A7 - solute carrier family 38 member 7 Gene

SLC38A7 - solute carrier family 38 member 7 Gene

中文名称:溶质载体家族 38 成员 7

种属: Homo sapiens

同用名: SNAT7

基因 ID: 55238 | 基因类型: protein coding

关于 SLC38A7

Cytogenetic location: 16q21 Genomic coordinates (GRCh38): 16:58,665,109-58,684,770 (from NCBI)

This gene has 16 transcripts (splice variants), 242 orthologues and 15 paralogues. Broad expression in testis (RPKM 12.2), brain (RPKM 4.6) and 23 other tissues.

功能概要

预计可启用 L-氨基酸跨膜转运蛋白活性。预计参与氨基酸跨膜转运和钠离子转运。预测位于轴突和神经细胞体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport and sodium ion transport. Predicted to be located in axon and neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022]

SLC38A7 基因产物(6)

mRNA Protein Name
NM_001308384.2 NP_001295313.1 putative sodium-coupled neutral amino acid transporter 7 isoform 2
NM_001369608.1 NP_001356537.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
NM_001369609.1 NP_001356538.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
NM_001369610.1 NP_001356539.1 putative sodium-coupled neutral amino acid transporter 7 isoform 2
NM_001369611.1 NP_001356540.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
NM_018231.3 NP_060701.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-asparagine:sodium symporter activity IDA
IDA: 通过直接分析推断
28416685 GOA
enables L-glutamine:sodium symporter activity IDA
IDA: 通过直接分析推断
28416685 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in asparagine transport IDA
IDA: 通过直接分析推断
28416685 GOA
involved in glutamine transport IDA
IDA: 通过直接分析推断
28416685 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in lysosomal membrane IDA
IDA: 通过直接分析推断
35561222 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SLC38A7 蛋白结构

Aa_trans

Aa_trans: Transmembrane amino acid transporter protein (50 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 462 a.a.
蛋白主名 其他名称

putative sodium-coupled neutral amino acid transporter 7

Sodium-coupled neutral amino acid transporter 7

SLC38A7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SLC38A7 Q9NVC3 IL10RA Homo sapiens Q13651
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 IL10RA Homo sapiens Q13651
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 LYVE1 Homo sapiens Q9Y5Y7
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 LYVE1 Homo sapiens Q9Y5Y7
Validated Y2H
32296183
Intra SLC38A7 Q9NVC3 LYVE1 Homo sapiens Q9Y5Y7
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 ACBD5 Homo sapiens Q5T8D3-2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 ACBD5 Homo sapiens Q5T8D3-2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SLC6A15 Homo sapiens Q9H2J7
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SLC6A15 Homo sapiens Q9H2J7
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SPINT1 Homo sapiens O43278-2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SPINT1 Homo sapiens O43278-2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 ODF4 Homo sapiens Q2M2E3
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 ODF4 Homo sapiens Q2M2E3
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 AQP2 Homo sapiens P41181
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 AQP2 Homo sapiens P41181
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra SLC38A7 Q9NVC3 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 AQP9 Homo sapiens O43315
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 AQP9 Homo sapiens O43315
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 EVI2B Homo sapiens P34910-2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 EVI2B Homo sapiens P34910-2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 BTNL9 Homo sapiens Q6UXG8-3
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 BTNL9 Homo sapiens Q6UXG8-3
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SHISAL1 Homo sapiens Q3SXP7
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SHISAL1 Homo sapiens Q3SXP7
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SYPL2 Homo sapiens Q5VXT5-2
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SYPL2 Homo sapiens Q5VXT5-2
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 APH1A Homo sapiens Q96BI3
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 APH1A Homo sapiens Q96BI3
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 HHLA2 Homo sapiens Q9UM44
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 HHLA2 Homo sapiens Q9UM44
Validated Y2H
32296183
Intra SLC38A7 Q9NVC3 HHLA2 Homo sapiens Q9UM44
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 CLEC10A Homo sapiens Q8IUN9
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 CLEC10A Homo sapiens Q8IUN9
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Array
25416956
Intra SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Prey Pooling
25416956
Intra SLC38A7 Q9NVC3 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
Intra SLC38A7 Q9NVC3 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 TSPAN8 Homo sapiens P19075
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 TSPAN8 Homo sapiens P19075
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 EDA Homo sapiens Q92838
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 EDA Homo sapiens Q92838
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 MMGT1 Homo sapiens Q8N4V1
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 MMGT1 Homo sapiens Q8N4V1
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 PANX1 Homo sapiens Q96RD7
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 PANX1 Homo sapiens Q96RD7
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 YIPF6 Homo sapiens Q96EC8
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 YIPF6 Homo sapiens Q96EC8
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra SLC38A7 Q9NVC3 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 CREB3L3 Homo sapiens Q68CJ9
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 CREB3L3 Homo sapiens Q68CJ9
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 SLC30A2 Homo sapiens Q9BRI3
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 SLC30A2 Homo sapiens Q9BRI3
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 LY6G6C Homo sapiens O95867
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 LY6G6C Homo sapiens O95867
Y2H Array
32296183
Intra SLC38A7 Q9NVC3 ERP29 Homo sapiens P30040
Y2H Prey Pooling
32296183
Intra SLC38A7 Q9NVC3 ERP29 Homo sapiens P30040
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Triple-Receptor Negative Breast Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC38A7 VGNC VGNC:34854
Felis catus SLC38A7 VGNC VGNC:65350
Macaca mulatta SLC38A7 VGNC VGNC:77570
Mus musculus SLC38A7 MGD MGI:2679005
Rattus norvegicus SLC38A7 RGD RGD:1303268
Canis familiaris SLC38A7 VGNC VGNC:46397