SLC14A2 - solute carrier family 14 member 2 Gene

中文名称：溶质载体家族 14 成员 2

种属: Homo sapiens

同用名: UT2; UTA; UTR; HUT2; UT-A2; hUT-A6

关于 SLC14A2

功能概要

该基因编码的蛋白质属于尿素转运蛋白家族。在哺乳动物细胞中，尿素是氮分解代谢的主要终产物，在尿浓缩机制中起着重要作用。这种蛋白质在肾脏的内髓质中表达，并介导跨内髓质集合管的快速跨上皮尿素转运。已发现该基因的可变剪接转录物变体。[RefSeq 提供，2011 年 9 月]

The protein encoded by this gene belongs to the Urea Transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]