1. Gene
  2. CDCA3 - cell division cycle associated 3 Gene

CDCA3 - cell division cycle associated 3 Gene

中文名称:细胞分裂周期相关 3

种属: Homo sapiens

同用名: GRCC8; TOME1; TOME-1

基因 ID: 83461 | 基因类型: protein coding

关于 CDCA3

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,844,798-6,851,286 (from NCBI)

This gene has 12 transcripts (splice variants) and 176 orthologues. Broad expression in testis (RPKM 6.4), duodenum (RPKM 3.8) and 20 other tissues.

功能概要

预计参与细胞分裂和蛋白质泛素化。位于 adherens 路口。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in cell division and protein ubiquitination. Located in adherens junction. [provided by Alliance of Genome Resources, Apr 2022]

CDCA3 基因产物(5)

mRNA Protein Name
NM_001297602.3 NP_001284531.1 cell division cycle-associated protein 3 isoform 2
NM_001297603.3 NP_001284532.1 cell division cycle-associated protein 3 isoform 3
NM_001297604.3 NP_001284533.1 cell division cycle-associated protein 3 isoform 4
NM_001331019.2 NP_001317948.1 cell division cycle-associated protein 3 isoform 5
NM_031299.7 NP_112589.1 cell division cycle-associated protein 3 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in adherens junction IDA
IDA: 通过直接分析推断
25468996 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cell division cycle-associated protein 3

gene-rich cluster protein C8

关联疾病

疾病名称 别名
Night Blindness, Congenital Stationary, Type 1h

Congenital Stationary Night Blindness 1h

CSNB1H

Congenital Stationary Night Blindness Type 1h

Night Blindness, Congenital Stationary, 1h

Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CDCA3 MGD MGI:1315198
Canis familiaris CDCA3 VGNC VGNC:39013
Felis catus CDCA3 VGNC VGNC:83523
Macaca mulatta CDCA3 VGNC VGNC:70711
Rattus norvegicus CDCA3 RGD RGD:1359093
Bos taurus CDCA3 VGNC VGNC:27084