2. Gene
  3. TEKT1 - tektin 1 Gene

TEKT1 - tektin 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：粘蛋白 1

种属: Homo sapiens

基因 ID: 83659 | 基因类型: protein coding

关于 TEKT1

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:6,797,993-6,831,729 (from NCBI)

This gene has 5 transcripts (splice variants), 194 orthologues and 5 paralogues. Restricted expression toward testis (RPKM 17.1).

功能概要

该基因产物属于蛋白质的 tektin 家族。 Tektins 包含一个细丝形成蛋白家族，这些蛋白与微管蛋白共同组装形成纤毛和鞭毛微管。该基因主要在睾丸和小鼠中表达，tektin 1 mRNA 定位于曲细精管中的精母细胞和圆形精子细胞，表明它可能在精子发生中发挥作用。[RefSeq 提供，2008 年 7 月]

This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

TEKT1 基因产物(1)

mRNA Protein Name
NM_053285.2 NP_444515.1 tektin-1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axonemal microtubule IDA
IDA: 通过直接分析推断
36191189 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TEKT1 蛋白结构

Tektin

Tektin: Tektin family (16 - 398)

  • 0
  • 100
  • 200
  • 300
  • 418 a.a.
蛋白主名 其他名称

tektin-1

TEKT1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TEKT1 Q969V4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
种属内
TEKT1 Q969V4 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
25416956
种属内
TEKT1 Q969V4 NCAPD3 Homo sapiens Q96FA6
Validated Y2H
25416956
种属内
TEKT1 Q969V4 NCAPD3 Homo sapiens Q96FA6
Y2H Array
25416956
种属内
TEKT1 Q969V4 NCAPD3 Homo sapiens Q96FA6
Y2H Prey Pooling
25416956
种属内
TEKT1 Q969V4 UNC45A Homo sapiens Q9H3U1
Validated Y2H
32296183
种属内
TEKT1 Q969V4 PRKAG1 Homo sapiens P54619
Y2H Array
25416956
种属内
TEKT1 Q969V4 C1orf74 Homo sapiens Q96LT6
Validated Y2H
32296183
种属内
TEKT1 Q969V4 CHD2 Homo sapiens O14647
Validated Y2H
25416956
种属内
TEKT1 Q969V4 CHD2 Homo sapiens O14647
Y2H Array
25416956
种属内
TEKT1 Q969V4 HNRNPH2 Homo sapiens P55795
Validated Y2H
25416956
种属内
TEKT1 Q969V4 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
种属内
TEKT1 Q969V4 VCL Homo sapiens P18206
Validated Y2H
25416956
种属内
TEKT1 Q969V4 VCL Homo sapiens P18206
Y2H Prey Pooling
25416956
种属内
TEKT1 Q969V4 SDCBP Homo sapiens O00560
Y2H Array
25416956
种属内
TEKT1 Q969V4 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
种属内
TEKT1 Q969V4 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
种属内
TEKT1 Q969V4 NME7 Homo sapiens Q9Y5B8
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Adult Spinal Cord Ependymoma
Ehlers-Danlos Syndrome, Kyphoscoliotic Type, 1

Nevo Syndrome

Eds Vi

Ehlers-Danlos Syndrome, Type Vi

Eds Via

Ehlers-Danlos Syndrome Type 6

EDSKSCL1

Eds6

Ehlers-Danlos Syndrome Kyphoscoliotic Type 1

Kyphoscoliotic Ehlers-Danlos Syndrome

Cutis Hyperelastica

Ehlers-Danlos Syndrome Type 6a

Ehlers-Danlos Syndrome Oculoscoliotic Type

Kyphoscoliotic Eds

Kyphoscoliotic Eds Due To Lysyl Hydroxylase 1 Deficiency

Kyphoscoliotic Ehlers-Danlos Syndrome Due To Lysyl Hydroxylase 1 Deficiency

Lysyl Hydroxylase-Deficient Eds

Ocular-Scoliotic Eds

Keds

Keds-Plod1

Ehlers-Danlos Syndrome, Kyphoscoliotic Type 1

Ehlers-Danlos Syndrome, Ocular-Scoliotic Type

Ehlers-Danlos Syndrome, Type Via, Formerly

Eds6a, Formerly

Eds 6

Eds, Kyphoscoliotic Type

Eds, Oculoscoliotic Type

Ehlers-Danlos Syndrome, Kyphoscoliosis Type

Ehlers-Danlos Syndrome, Kyphoscoliotic Type

Ehlers-Danlos Syndrome, Oculoscoliotic Type

Eds6a

Ehlers-Danlos Syndrome 6

Ehlers-Danlos Syndrome Kyphoscoliotic Type
Brain Ependymoma

Ependymal Tumor Of Brain

Ependymoma Of Brain
Spondyloepimetaphyseal Dysplasia, Sponastrime Type

Sponastrime Dysplasia

Spondylar And Nasal Alterations With Striated Metaphyses

SEMDSP

Short-Limb Dwarfism With Saddle Nose, Spinal Alterations, And Metaphyseal Striation

Spondylar And Nasal Alterations-Striated Metaphyses Syndrome

Spondyloepimetaphyseal Dysplasia Sponastrime Type

Short Limb Dwarfism With Saddle Nose, Spinal Alterations, And Metaphyseal Striation

Spondylar And Nasal Changes With Striations Of The Metaphyses Dysplasia

Short Limb Dwarfism With Saddle Nose, Spinal Alterations And Metaphyseal Striation

Dysplasia, Spondyloepimetaphyseal, Sponastrime Type
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
Visceral Heterotaxy

Situs Ambiguus

Heterotaxia

Heterotaxy Syndrome

Heterotaxy

Lateralization Defect

Situs Ambiguous

Left Isomerism

Htx

Ivemark Syndrome

Right Isomerism

Situs Ambiguus Viscerum

Incomplete Situs Inversus

Partial Situs Inversus

Heterotaxy, Visceral

Asplenia Syndrome

Bilateral Left-Sidedness

Polysplenia Syndrome

Moller Syndrome
Epilepsy, Myoclonic Juvenile

Juvenile Myoclonic Epilepsy

Janz Syndrome

Jme

Myoclonic Epilepsy, Juvenile, Susceptibility To, 1

EJM

Myoclonic Epilepsy, Juvenile

Petit Mal, Impulsive

Myoclonic Epilepsy, Juvenile 1

Myoclonic Epilepsy, Juvenile, 1

Adolescent Myoclonic Epilepsy

Juvenile Myoclonus Epilepsy

Juvenile Myoclonic Epilepsy 1

EJM1

Petit Mal Impulsive

Susceptibility To Juvenile Myoclonic Epilepsy 1

Myoclonic Epilepsy Juvenile

Epilepsy, Myoclonic, Juvenile

Myoclonic Epilepsy Of Janz

Jme - [Juvenile Myoclonic Epilepsy]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14356 TEKT1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta TEKT1 VGNC VGNC:78387
Felis catus TEKT1 VGNC VGNC:66065
Rattus norvegicus TEKT1 RGD RGD:619913
Bos taurus TEKT1 VGNC VGNC:35736
Mus musculus TEKT1 MGD MGI:1333819
Canis familiaris TEKT1 VGNC VGNC:47242
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z