RBP5 - retinol binding protein 5 Gene

中文名称：视黄醇结合蛋白 5

种属: Homo sapiens

同用名: CRBP3; CRBPIII; HRBPiso; CRBP-III

基因 ID: 83758 | 基因类型: protein coding

关于 RBP5

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,115,736-7,130,005 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 240 orthologues and 15 paralogues. Biased expression in kidney (RPKM 131.3), liver (RPKM 58.1) and 3 other tissues.

功能概要

该基因编码的蛋白质是一种在肾脏和肝脏中高度表达的细胞视黄醇结合蛋白。肝细胞癌中编码蛋白的下调与肿瘤体积大和患者存活率低有关。[RefSeq 提供，2016 年 7 月]

The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016]

RBP5 基因产物(2)

mRNA	Protein	Name
NM_001329454.2	NP_001316383.1	retinol-binding protein 5 isoform 2
NM_031491.4	NP_113679.1	retinol-binding protein 5 isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RBP5 蛋白结构

Lipocalin

0
100
135 a.a.

蛋白主名

其他名称

retinol-binding protein 5

cellular retinol-binding protein III

重组 RBP5 蛋白

目录号	产品名	蛋白编号	纯度
HY-P71250	RBP5 Protein, Human	P82980 (M1-R135)	≥95%

关联疾病

疾病名称

别名

Total Anomalous Pulmonary Venous Return 1

Scimitar Syndrome	Total Anomalous Pulmonary Venous Return
Anomalous Pulmonary Venous Return	Scimitar Anomaly
TAPVR1	Apvr
Halasz Syndrome	Hypogenetic Lung Syndrome
Pulmonary Venolobar Syndrome	TAPVR
Congenital Total Pulmonary Venous Return Anomaly	Congenital Venolobar Syndrome
Mirror-Image Lung Syndrome	Vena Cava Bronchovascular Syndrome
Pulmonary Venous Return Anomaly	Congenital Pulmonary Venolobar Syndrome
Epibronchial Right Pulmonary Vein Syndrome

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

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RBP5 - retinol binding protein 5 Gene

关于 RBP5

功能概要

RBP5 基因产物(2)

RBP5 蛋白结构

重组 RBP5 蛋白

关联疾病

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RBP5 - retinol binding protein 5 Gene

关于 RBP5

功能概要

RBP5 基因产物(2)

RBP5 蛋白结构

重组 RBP5 蛋白

关联疾病

相关产品

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

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