2. Gene
  3. Ppp1r9b - protein phosphatase 1, regulatory subunit 9B Gene

Ppp1r9b - protein phosphatase 1, regulatory subunit 9B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Neb2

基因 ID: 84686 | 基因类型: protein coding

关于 Ppp1r9b

功能概要

Enables several functions, including D2 Dopamine Receptor binding activity; Enzyme binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; pallium development; and positive regulation of protein localization to cell periphery. Located in several cellular components, including dendritic spine; growth cone; and postsynaptic density. Biomarker of Parkinson's disease. Orthologous to human PPP1R9B (protein Phosphatase 1 regulatory subunit 9B). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1r9b 基因产物(2)

mRNA Protein Name
NM_053474.2 NP_445926.1 neurabin-2
NM_053474.2 NP_445926.1 neurabin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables D2 dopamine receptor binding IPI
IPI: 通过物理相互作用推断
10391935 RGD
enables actin binding IDA
IDA: 通过直接分析推断
15135218 RGD
enables actin filament binding IDA
IDA: 通过直接分析推断
12417592 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
11182094 RGD
enables nucleic acid binding EXP
EXP: 通过实验结果推断
18028445 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9514910 RGD
enables protein kinase activity IDA
IDA: 通过直接分析推断
9653190 RGD
enables protein phosphatase 1 binding IDA
IDA: 通过直接分析推断
9275233 RGD
enables protein phosphatase 1 binding IPI
IPI: 通过物理相互作用推断
12016225 RGD
enables protein phosphatase inhibitor activity IDA
IDA: 通过直接分析推断
12016225 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
12270929 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
16025302 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament depolymerization IEP
IEP: 通过表达模式推断
10620493 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
10620493 RGD
involved in cellular response to estradiol stimulus IEP
IEP: 通过表达模式推断
16951259 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
16951259 RGD
involved in cellular response to peptide IEP
IEP: 通过表达模式推断
21123436 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16844384 RGD
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
9275233 RGD
involved in developmental process involved in reproduction IEP
IEP: 通过表达模式推断
18096161 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
21123436 RGD
involved in learning IEP
IEP: 通过表达模式推断
24069387 RGD
involved in male mating behavior IEP
IEP: 通过表达模式推断
18726914 RGD
involved in positive regulation of protein localization IDA
IDA: 通过直接分析推断
18216290 RGD
involved in positive regulation of protein localization to actin cortical patch IMP
IMP: 通过突变表型推断
18216290 RGD
involved in positive regulation of protein localization to plasma membrane IDA
IDA: 通过直接分析推断
9514910 RGD
involved in protein localization to actin cytoskeleton IMP
IMP: 通过突变表型推断
18216290 RGD
involved in protein localization to cell periphery IMP
IMP: 通过突变表型推断
18216290 RGD
involved in reproductive system development IEP
IEP: 通过表达模式推断
18096161 RGD
involved in response to L-phenylalanine derivative IEP
IEP: 通过表达模式推断
12112407 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
17443789 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
19932152 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
17443789 RGD
involved in response to immobilization stress IEP
IEP: 通过表达模式推断
22128856 RGD
involved in response to kainic acid IEP
IEP: 通过表达模式推断
17443789 RGD
involved in response to nicotine IEP
IEP: 通过表达模式推断
22959963 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17408863 RGD
involved in response to prostaglandin E IEP
IEP: 通过表达模式推断
23054057 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
20399784 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
22160164 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
10514494 RGD
located in cytoplasmic side of dendritic spine plasma membrane IDA
IDA: 通过直接分析推断
9275233 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
15135218 RGD
located in dendritic spine head IDA
IDA: 通过直接分析推断
9275233 RGD
located in dendritic spine membrane IDA
IDA: 通过直接分析推断
9275233 RGD
located in dendritic spine neck IDA
IDA: 通过直接分析推断
9275233 RGD
is active in extrinsic component of postsynaptic membrane IDA
IDA: 通过直接分析推断
9275233 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
9275233 RGD
located in growth cone IDA
IDA: 通过直接分析推断
12270929 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10620493 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
9275233 RGD
is active in spine apparatus IDA
IDA: 通过直接分析推断
9275233 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neurabin-2

PP1bp134

neurabin-II

neural tissue-specific F-actin-binding protein II

nuerabin 2

p130

spinophilin

Ppp1r9b 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Ppp1r9b O35274 PPP1CA Homo sapiens P62136
Anti Tag CoIP
25785436
种属间
Ppp1r9b O35274 PTPN6 Homo sapiens P29350
Anti Tag CoIP
25785436
种属内
Ppp1r9b O35274 Drd2 Rattus norvegicus P61169
Y2H
10391935
种属内
Ppp1r9b O35274 Ppp1cc Rattus norvegicus P63088
Pull Down
10391935
种属内
Ppp1r9b O35274 Ppp1cc Rattus norvegicus P63088
Imaging
18216290
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11006 PPP1R9B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp1r9b NCBI NCBI:84687
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