CBLN1 - cerebellin 1 precursor Gene

中文名称：小脑蛋白 1 前体

种属: Homo sapiens

关于 CBLN1

功能概要

该基因编码一种小脑特异性前体蛋白，前小脑蛋白，与补体成分 C1qB 的球状 (非胶原样) 结构域相似。 Precereblin 经过加工后可产生多种衍生物，包括十六肽小脑蛋白，它在浦肯野细胞的突触后结构中高度富集。在人类和大鼠的肾上腺中也发现了 Cerebellin，它已被证明可以增强该腺体的分泌活动。[RefSeq 提供，2008 年 8 月]

This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008]