NAPA - NSF attachment protein alpha Gene

中文名称：NSF 附着蛋白α

种属: Homo sapiens

同用名: SNAPA

关于 NAPA

功能概要

该基因编码可溶性 NSF 附着蛋白 (SNAP) 家族的成员。作为 20S NSF-SNAP-SNARE 复合物的一部分，SNAP 蛋白在囊泡与靶膜的对接和融合中起着关键作用。编码的蛋白质通过介导 N-乙基马来酰亚胺敏感因子 (NSF) 与囊泡相关和膜相关 SNAP 受体 (SNARE) 复合物的相互作用，并刺激 NSF 的 ATP 酶活性，从而在膜融合的完成中发挥作用。已观察到该基因的可变剪接转录物变体。[RefSeq 提供，2011 年 6 月]

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]