2. Gene
  3. NXPE3 - neurexophilin and PC-esterase domain family member 3 Gene

NXPE3 - neurexophilin and PC-esterase domain family member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：neurexophilin 和 PC 酯酶域家族成员 3

种属: Homo sapiens

同用名: FAM55C; MST115; MSTP115

基因 ID: 91775 | 基因类型: protein coding

关于 NXPE3

This gene has 33 transcripts (splice variants), 504 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 6.4), lymph node (RPKM 5.0) and 24 other tissues.

功能概要

该基因编码神经肽样糖蛋白的 neurexophilin 家族成员。编码的蛋白质包含一个可变的 N 末端结构域、一个高度保守的嗜神经细胞蛋白和 PC 酯酶 (NXPE) 中央结构域、一个短连接区域和一个富含半胱氨酸的 C 末端结构域。这种蛋白质结合 alpha neurexins，一组促进树突和轴突之间粘附的突触前跨膜受体。可变剪接导致多个转录本变体。[RefSeq 提供，2017 年 2 月]

This gene encodes a member of the neurexophilin family of neuropeptide-like glycoproteins. The encoded protein contains a variable N-terminal domain, a highly conserved neurexophilin and PC-esterase (NXPE) central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein binds alpha neurexins, a group of presynaptic transmembrane receptors that promote adhesion between dendrites and axons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

NXPE3 基因产物(11)

mRNA Protein Name
NM_001134456.2 NP_001127928.1 NXPE family member 3 isoform 1 precursor
NM_001348990.2 NP_001335919.1 NXPE family member 3 isoform 1 precursor
NM_001348991.2 NP_001335920.1 NXPE family member 3 isoform 1 precursor
NM_001348992.2 NP_001335921.1 NXPE family member 3 isoform 1 precursor
NM_001348993.2 NP_001335922.1 NXPE family member 3 isoform 1 precursor
NM_001348994.2 NP_001335923.1 NXPE family member 3 isoform 1 precursor
NM_001348995.2 NP_001335924.1 NXPE family member 3 isoform 1 precursor
NM_001348996.2 NP_001335925.1 NXPE family member 3 isoform 2
NM_001348997.2 NP_001335926.1 NXPE family member 3 isoform 2
NM_001348998.2 NP_001335927.1 NXPE family member 3 isoform 2
NM_145037.4 NP_659474.1 NXPE family member 3 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NXPE3 蛋白结构

Neurexophilin

Neurexophilin: Neurexophilin (74 - 284)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 559 a.a.
蛋白主名 其他名称

NXPE family member 3

family with sequence similarity 55, member C

NXPE3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NXPE3 Q969Y0 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra NXPE3 Q969Y0 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra NXPE3 Q969Y0 ERVFRD-1 Homo sapiens P60508
Y2H Prey Pooling
32296183
Intra NXPE3 Q969Y0 ERVFRD-1 Homo sapiens P60508
Y2H Array
32296183
Intra NXPE3 Q969Y0 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra NXPE3 Q969Y0 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra NXPE3 Q969Y0 MRM1 Homo sapiens Q6IN84
Y2H Prey Pooling
32296183
Intra NXPE3 Q969Y0 MRM1 Homo sapiens Q6IN84
Y2H Array
32296183
Intra NXPE3 Q969Y0 OS9 Homo sapiens Q13438
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09716 NXPE3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus NXPE3 VGNC VGNC:32380
Mus musculus NXPE3 MGD MGI:2686598
Rattus norvegicus NXPE3 RGD RGD:1584648
Macaca mulatta NXPE3 VGNC VGNC:75476
Felis catus NXPE3 VGNC VGNC:63938
Canis familiaris NXPE3 VGNC VGNC:44075
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