1. Gene
  2. ASB16 - ankyrin repeat and SOCS box containing 16 Gene

ASB16 - ankyrin repeat and SOCS box containing 16 Gene

中文名称:含锚蛋白重复和 SOCS 盒 16

种属: Homo sapiens

基因 ID: 92591 | 基因类型: protein coding

关于 ASB16

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,170,704-44,179,084 (from NCBI)

This gene has 3 transcripts (splice variants), 186 orthologues and 7 paralogues. Ubiquitous expression in spleen (RPKM 1.6), prostate (RPKM 1.5) and 25 other tissues.

功能概要

由该基因编码的蛋白质是锚蛋白重复序列和含有 SOCS 盒 (ASB) 的蛋白质家族的成员。它们包含锚蛋白重复序列和 SOCS 框域。 SOCS 盒用于将细胞因子信号转导抑制因子 (SOCS) 蛋白及其结合伙伴与 elongin B 和 C 复合物偶联,可能靶向它们进行降解。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jul 2008]

ASB16 基因产物(1)

mRNA Protein Name
NM_080863.5 NP_543139.4 ankyrin repeat and SOCS box protein 16
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17474147 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ASB16 蛋白结构

Ank

Ank: Ankyrin repeat (114 - 140)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (147 - 239)

Ank_5

Ank_5: Ankyrin repeats (many copies) (270 - 324)

SOCS_box

SOCS_box: SOCS box (408 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 453 a.a.
蛋白主名 其他名称

ankyrin repeat and SOCS box protein 16

ankyrin repeat and SOCS box-containing protein 16

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ASB16 RGD RGD:1563878
Canis familiaris ASB16 VGNC VGNC:38160
Macaca mulatta ASB16 VGNC VGNC:99119
Mus musculus ASB16 MGD MGI:2654437
Bos taurus ASB16 VGNC VGNC:26193
Felis catus ASB16 VGNC VGNC:98762