1. Gene
  2. TRIP10 - thyroid hormone receptor interactor 10 Gene

TRIP10 - thyroid hormone receptor interactor 10 Gene

中文名称:甲状腺激素受体相互作用因子 10

种属: Homo sapiens

同用名: STP; CIP4; HSTP; STOT; TRIP-10

基因 ID: 9322 | 基因类型: protein coding

关于 TRIP10

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,739,680-6,751,530 (from NCBI)

This gene has 13 transcripts (splice variants), 253 orthologues and 2 paralogues. Ubiquitous expression in esophagus (RPKM 54.6), fat (RPKM 34.4) and 22 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与肌动蛋白细胞骨架组织;内吞作用;和信号转导。位于核质中。亨廷顿病的生物标志物。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in actin Cytoskeleton organization; endocytosis; and signal transduction. Located in nucleoplasm. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Apr 2022]

TRIP10 基因产物(3)

mRNA Protein Name
NM_001288962.2 NP_001275891.1 cdc42-interacting protein 4 isoform 1
NM_001288963.3 NP_001275892.1 cdc42-interacting protein 4 isoform 3
NM_004240.4 NP_004231.1 cdc42-interacting protein 4 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17512409 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16318909 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TRIP10 蛋白结构

FCH

FCH: Fes/CIP4, and EFC/F-BAR homology domain (1 - 94)

SH3_1

SH3_1: SH3 domain (546 - 593)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 601 a.a.
蛋白主名 其他名称

cdc42-interacting protein 4

TR-interacting protein 10

TRIP10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRIP10 Q15642 ARHGAP44 Homo sapiens Q17R89-2 25416956
种属内
TRIP10 Q15642 ARHGAP44 Homo sapiens Q17R89-2 25416956
种属内
TRIP10 Q15642 WASF1 Homo sapiens Q92558 25416956
种属内
TRIP10 Q15642 ARHGAP17 Homo sapiens Q68EM7 25416956
种属内
TRIP10 Q15642 SH3BP1 Homo sapiens Q9Y3L3 25416956
种属内
TRIP10 Q15642 SH3BP1 Homo sapiens Q9Y3L3 25416956
种属内
TRIP10 Q15642 SMARCE1 Homo sapiens Q969G3 25416956
种属内
TRIP10 Q15642 SMARCE1 Homo sapiens Q969G3 25416956
种属内
TRIP10 Q15642 FASLG Homo sapiens P48023 16318909
种属内
TRIP10 Q15642 FASLG Homo sapiens P48023 16318909
种属内
TRIP10 Q15642 FASLG Homo sapiens P48023 16318909
种属内
TRIP10 Q15642 RHOJ Homo sapiens Q9H4E5 25416956
种属内
TRIP10 Q15642 TINF2 Homo sapiens Q9BSI4 21044950
种属内
TRIP10 Q15642 TINF2 Homo sapiens Q9BSI4 21044950
种属内
TRIP10 Q15642 TRIP10 Homo sapiens Q15642 25416956
种属内
TRIP10 Q15642 TRIP10 Homo sapiens Q15642 17512409
种属内
TRIP10 Q15642 TRIP10 Homo sapiens Q15642
EM
18329367
种属内
TRIP10 Q15642 TRIP10 Homo sapiens Q15642 17512409
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 TRIP10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76260 TRIP10/CIP4 Protein, Human (sf9, His) Q15642 (M1-N545) ≥95%

TRIP10 抗体

目录号 产品名 应用 反应物种
HY-P82758 CIP4 Antibody (YA2503) WB Human, Mouse, Rat

关联疾病

疾病名称 别名
Wiskott-Aldrich Syndrome

WAS

Eczema-Thrombocytopenia-Immunodeficiency Syndrome

Immunodeficiency 2

Aldrich Syndrome

Imd2

Wiskott-Aldrich Syndrome 1

Was1

Wiskott Syndrome

Wiskott Aldrich Syndrome

Eczema Thrombocytopenia Immunodeficiency Syndrome

Imd 2

Myopathy, Centronuclear, 2

Myopathy, Centronuclear, Autosomal Recessive

Autosomal Recessive Centronuclear Myopathy

CNM2

Centronuclear Myopathy 2

Ar-Cnm

Myotubular Myopathy, Autosomal Recessive

Autosomal Recessive Myotubular Myopathy

Centronuclear Myopathy Autosomal Recessive

Myopathy, Centronuclear, Type 2

Hypochondriasis

Hypochondriacal Disorder

Hypochondria

Hypochondriacal Neurosis

Illness Anxiety Disorder

Health Anxiety Disorder

Hypochondriacal Reaction

Chronic Recurrent Multifocal Osteomyelitis

Chronic Multifocal Osteomyelitis

CRMO

Cmo

Cno/Crmo

Chronic Nonbacterial Osteomyelitis/Chronic Recurrent Multifocal Osteomyelitis

Osteomyelitis, Chronic Multifocal

Multifocal Osteomyelitis, Chronic

Chronic Osteomyelitis

Chronic Multifocal Osteomyelitis, Unspecified Site

Crmo - [Chronic Multifocal Osteomyelitis]

Chronic Osteomyelitis With Draining Sinus, Unspecified Site

Bone Fistula With Chronic Osteomyelitis

Familial Hypocalciuric Hypercalcemia

Familial Benign Hypercalcemia

Fbh

Fbhh

Fhh

Familial Benign Hypocalciuric Hypercalcemia

Hypocalciuric Hypercalcemia, Familial, Type 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus TRIP10 MGD MGI:2146901
Canis familiaris TRIP10 VGNC VGNC:47844
Macaca mulatta TRIP10 VGNC VGNC:78646
Bos taurus TRIP10 VGNC VGNC:106998
Rattus norvegicus TRIP10 RGD RGD:621145
Felis catus TRIP10 VGNC VGNC:66558
Others TRIP10 NCBI