2. Gene
  3. MTSS1 - MTSS I-BAR domain containing 1 Gene

MTSS1 - MTSS I-BAR domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 MTSS I-BAR 域 1

种属: Homo sapiens

同用名: MIM; MIMA; MIMB

基因 ID: 9788 | 基因类型: protein coding

关于 MTSS1

Cytogenetic location: 8q24.13 Genomic coordinates (GRCh38): 8:124,550,784-124,728,473 (from NCBI)

This gene has 18 transcripts (splice variants), 275 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 5.7), adrenal (RPKM 5.6) and 25 other tissues.

功能概要

启用肌动蛋白单体结合活性；相同的蛋白质结合活性；和信号受体结合活性。预计参与细胞对流体剪切应力的反应；上皮细胞增殖的负调节；和泌尿生殖系统发育。预计在几个过程的上游或内部起作用，包括肌动蛋白丝聚合；粘附连接维护；和镁离子稳态。位于肌动蛋白细胞骨架中。 [由基因组资源联盟提供，2022 年 4 月]

Enables actin monomer binding activity; identical protein binding activity; and signaling receptor binding activity. Predicted to be involved in cellular response to fluid shear stress; negative regulation of epithelial cell proliferation; and urogenital system development. Predicted to act upstream of or within several processes, including actin filament polymerization; adherens junction maintenance; and magnesium ion homeostasis. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

MTSS1 基因产物(12)

mRNA Protein Name
NM_001282971.2 NP_001269900.1 protein MTSS 1 isoform 1
NM_001282974.2 NP_001269903.1 protein MTSS 1 isoform 3
NM_001363294.2 NP_001350223.1 protein MTSS 1 isoform 4
NM_001363295.2 NP_001350224.1 protein MTSS 1 isoform 5
NM_001363296.2 NP_001350225.1 protein MTSS 1 isoform 6
NM_001363297.2 NP_001350226.1 protein MTSS 1 isoform 7
NM_001363298.2 NP_001350227.1 protein MTSS 1 isoform 8
NM_001363299.2 NP_001350228.1 protein MTSS 1 isoform 9
NM_001363300.2 NP_001350229.1 protein MTSS 1 isoform 10
NM_001363301.2 NP_001350230.1 protein MTSS 1 isoform 11
NM_001363302.2 NP_001350231.1 protein MTSS 1 isoform 12
NM_014751.6 NP_055566.3 protein MTSS 1 isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin monomer binding IDA
IDA: 通过直接分析推断
12570871 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
14752106 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15383276 GOA
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
12570871 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
12570871 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MTSS1 蛋白结构

IMD

IMD: IRSp53/MIM homology domain (16 - 237)

WH2

WH2: WH2 motif (725 - 750)

  • 0
  • 200
  • 400
  • 600
  • 755 a.a.
蛋白主名 其他名称

protein MTSS 1

MTSS1, I-BAR domain containing

重组 MTSS1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75930 MTSS1 Protein, Human (His) EAW92073 (M1-S250) ≥95%

关联疾病

疾病名称 别名
Oropharyngeal Anthrax
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08820 MTSS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus MTSS1 MGD MGI:2384818
Canis familiaris MTSS1 VGNC VGNC:43493
Bos taurus MTSS1 VGNC VGNC:31752
Macaca mulatta MTSS1 VGNC VGNC:74995
Felis catus MTSS1 VGNC VGNC:63660
Rattus norvegicus MTSS1 RGD RGD:1309883
Others MTSS1 NCBI
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