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  3. hCAI/II-IN-9

hCAI/II-IN-9是一种碳酸酐酶抑制剂,具有对人类碳酸酐酶I、II、IX和XII亚型的抑制活性。hCAI/II-IN-9对hCA I的抑制常数(Ki)在7.9-894 nM范围内,对hCA II的抑制常数在7.5-1645 nM范围内,对hCA IX的抑制常数在5.0-240 nM范围内,而对hCA XII的抑制常数则在0.47-2.83 nM范围内。hCAI/II-IN-9可能在抑制涉及这些碳酸酐酶亚型的多种病理中具有潜在的应用价值。

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hCAI/II-IN-9 Chemical Structure

hCAI/II-IN-9 Chemical Structure

CAS No. : 175014-68-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hCAI/II-IN-9 is a carbonic anhydrase inhibitor with inhibitory activity against human carbonic anhydrase isoforms I, II, IX, and XII. The inhibition constants (Ki) of hCAI/II-IN-9 for hCA I are in the range of 7.9-894 nM, for hCA II are in the range of 7.5-1645 nM, for hCA IX are in the range of 5.0-240 nM, and for hCA XII are in the range of 0.47-2.83 nM. hCAI/II-IN-9 may have potential applications in inhibiting a variety of pathologies involving these carbonic anhydrase isoforms[1].

分子量

336.32

Formula

C13H12N4O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

hCAI/II-IN-9 相关分类

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
hCAI/II-IN-9
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HY-129986
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