2. Metabolic Enzyme/Protease
  3. Proteasome
  4. Immunoproteasome activator 1

Immunoproteasome activator 1 (compound A) 是一种选择性的免疫蛋白酶体激活剂，可以使单个 MHC-I 结合肽的呈递增加超 100 倍。Immunoproteasome activator 1 与蛋白酶体结构亚单位 PSMA1 结合，并促进蛋白酶体激活物 PA28α/β (PSME1/PSME2) 与免疫蛋白酶体的结合。

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Immunoproteasome activator 1 Chemical Structure

Immunoproteasome activator 1 Chemical Structure

CAS No. : 901728-48-1

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Immunoproteasome activator 1 相关抗体

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生物活性

Immunoproteasome activator 1 (compound A) is a selective immunoproteasome activator that increases the presentation of individual MHC-I–bound peptides by over 100-fold. Immunoproteasome activator 1 binds to the proteasome structural subunit PSMA1 and promotes the association of the proteasome activator PA28α/β (PSME1/PSME2) with immunoproteasomes[1].

分子量

401.46

Formula

C24H23N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Immunoproteasome activator 1 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Immunoproteasome activator 1901728-48-1Immunoproteasome activator1Immunoproteasome activator-1Proteasomeimmunoproteasome activatorMHC-I–bound peptidePSMA1PA28α/βInhibitorinhibitorinhibit

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Immunoproteasome activator 1
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HY-162965
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