2. Anti-infection Metabolic Enzyme/Protease NF-κB Cell Cycle/DNA Damage
  3. Parasite Tyrosinase NF-κB CDK
  4. Kojic acid (Standard)

Kojic acid (Standard)  (Synonyms: 曲酸 (Standard))

目录号: HY-W050154R 纯度: ≥98%
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摩尔计算器

Kojic acid (Standard) 是 Kojic acid 的分析标准品。本产品用于研究及分析应用。Kojic acid 是由 Aspergillus oryzae 产生的物质，具有抗肿瘤、抗虫、抗菌、抗氧化、防辐射等多种生物活性。Kojic acid 具有酪氨酸酶抑制活性，通过捕获与酪氨酸酶活性位点结合的铜离子防止其激活，酪氨酸酶是黑色素生物合成的核心酶，因此 Kojic acid 可以阻止黑色素产生。此外，Kojic acid 显示出对人角质形成细胞中 NF-κB 活性的潜在抑制作用，这种对 NF-κB 的抑制作用也可能与曲酸诱导的抗黑色素效应有关。Kojic acid 具有口服有效性也可被透皮吸收，由 Kojic acid 制备的纳米载体系统显示出对抗癌药物的有效递送。Kojic acid 有望用于癌症、感染疾病及美白等多领域研究。

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Kojic acid (Standard) Chemical Structure

Kojic acid (Standard) Chemical Structure

CAS No. : 501-30-4

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生物活性

Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields.

分子量

142.11

Formula

C₆H₆O₄
CAS 号
中文名称

曲酸 (Standard)
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Kojic acid (Standard) 相关分类

  • 摩尔计算器

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kojic acid (Standard)501-30-4曲酸 (Standard)ParasiteTyrosinaseNF-κBCDKNuclear factor-κBNuclear factor-kappaBCyclin dependent kinaseHCEC-B4G12?cellsB16-4A5 cellsHMV-II cellsβ-Amyloid (1-42)human (HY-P1363A)-Induced Mouse Model of Alzheimer's DiseaseAnti-aging activityAnti-cancer activityAnti-nematode activityAntimicrobial activityAntioxidant activityand Anti-inflammatory activity,Inhibitorinhibitorinhibit

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