1. GPCR/G Protein
  2. GnRH Receptor
  3. Lamprey LH-RH I

Lamprey LH-RH I 一种促性腺激素释放激素,提高血浆类固醇水平,刺激七鳃鳗排卵,对其他动物模型没有影响。

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Custom Peptide Synthesis

Lamprey LH-RH I Chemical Structure

Lamprey LH-RH I Chemical Structure

CAS No. : 102634-23-1

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models[1].

体外研究
(In Vitro)

Lamprey LH-RH I has a primary mechanism of transport to the pituitary is simple diffusion from neuronal terminals in the neurohypophysis to the adenohypophysis. An additional route is via secretion into the third ventricle and transport by tanycytes to the adenohypophysis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Lamprey LH-RH I (5-200 μg/kg; i.p.; single dose or twice) elevates plasma steroid levels and stimulates lamprey ovulation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female sea-run sea lampreys[1]
Dosage: 5 μg/kg, 50 μg/kg, 100 μg/kg, 200 μg/kg; dissolved in 0.6% NaCl in distilled water
Administration: Intraperitoneal injection; single dose or twice; observed for 30 days
Result: Significantly increased estradiol in a dose-related manner.
Resulted 80% of the lampreys ovulation at 200 or 100 μg/kg compared in a doserelated manner.
分子量

1226.34

Formula

C58H79N15O15

CAS 号
Sequence Shortening

{Glp}-HYSLEWKPG-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lamprey LH-RH I
目录号:
HY-P3673
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