2. Academic Validation
  3. New biologically active rubiginones from Streptomyces sp

New biologically active rubiginones from Streptomyces sp

  • J Antibiot (Tokyo). 2000 Apr;53(4):329-36. doi: 10.7164/antibiotics.53.329.
C Puder 1,  A Zeeck,  W Beil
Affiliations

Affiliation

  • 1 Institut für Organische Chemie, Universität Göttingen, Germany.
PMID: 10866213 DOI: 10.7164/antibiotics.53.329
Abstract

Four new polyketides, named rubiginone D2 (2), 4-O-acetyl-rubiginone D2 (3), rubiginone H (6) and rubiginone I (7) were isolated from the cultures of Streptomyces sp. (strain Gö N1/5). Their structures were established by a detailed spectroscopic analysis. The absolute configuration of 3 was determined by derivatization with chiral acids (Helmchen's method). The rubiginones inhibit the growth of some Gram-positive bacteria and are cytostatically active against different tumor cell lines.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z