2. Academic Validation
  3. Synthesis and fungicidal activity of N-2-(3-methoxy-4-propargyloxy)phenethyl amides. Part II: anti-oomycetic mandelamides

Synthesis and fungicidal activity of N-2-(3-methoxy-4-propargyloxy)phenethyl amides. Part II: anti-oomycetic mandelamides

  • Pest Manag Sci. 2006 May;62(5):446-51. doi: 10.1002/ps.1188.
Clemens Lamberth 1,  Fredrik Cederbaum,  Andre Jeanguenat,  Hans-Joachim Kempf,  Martin Zeller,  Ronald Zeun
Affiliations

Affiliation

  • 1 Syngenta AG, Crop Protection Research, Chemistry, Schwarzwaldallee 215, CH-4058 Basel, Switzerland. clemens.lamberth@syngenta.com
PMID: 16550505 DOI: 10.1002/ps.1188
Abstract

Novel types of anti-oomycetic compounds have been designed and prepared. The synthetic approach to these mandelamides is outlined. Biological data demonstrate their high efficacy against important plant diseases such as tomato and potato late blight (Phytophthora infestans De Bary) and grape downy mildew (Plasmopara viticola Berliner & de Toni). Structure-activity relationship studies are discussed. The new development product mandipropamid is presented.

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